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时间:2020-05-02
《右美托咪定在局部麻醉下颈椎后路手术中的应用.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、匡生且簋Q鲞筮Z期』ngSUMedJ,April2014,Vol40,No.7·825·论著右美托咪定在局部麻醉下颈椎后路手术中的应用邓莉嵇富海杨建平【摘要】目的评价右美托咪定在局部麻醉下颈椎后路手术中的镇静效果。方法将42例行颈椎后路手术的患者随机均分为两组:D组术前泵注右美托咪定0.5g/kg,继以0.3btg·k·m维持至术毕;C组给予等量生理盐水。记录入室后5min(T0)、切皮前(T1)、切皮后(T2)、手术开始后1h(T3)、2h(T4)及缝皮时(T5)的HR、MAP和Sp02。记录D组患者Ramsay评分。
2、观察术中降压药物的使用以及患者的配合程度,记录术后2h的VAS疼痛评分。结果D组T1一T5时HR和MAP均低于c组(P3、ncervicalspinaloperationbyposteriorapproachunderlocalanesthesiaD1GtJi,JIFuhai,YANGJianping.Department0fAnesthesiology,FirstAffiliatedHospital,SoochowUniversity,Suzhou215006,CHINA[Abstract]ObjectiveToevaluatetheefficiencyofdexmedetomidineforsedationduringcervicals4、pinaloperationviaposteriorapproachunderlocalanesthesia.MethodsForty-twopatientswereequallyrandomizedintotwogroupsofD(receiveddexmedetomidine0.5g/kgfor10minasaloadingdose,fo1lowedbyacontinuousinfusionat0.3g·kg·min)andC(receivedequalvolumeofnormalsaline).Thechanges5、ofMAP,HRandSpOzwererecordedonarrivalatoperatingroom(TO),beforeskinincision(T1),atskinincision(T2),in1hourafterincision(T3),in2hoursafterincision(T4)andatskinsuture(T5).RamsaysedationscaleofgroupDwasevaluatedandtheamountofantihypertensivedrugs,coordinationofthepat6、ients,andVASpainscorein2hoursafteroperationweremeasured.ResultsThevaluesofMAPandHRatT1toT5wereloweringroupDthanthoseingroupC(P<0.05).ComparedwithgroupC,thepatientsrequiredlessantmypertensivetreatment(P<0.O1)andshowedmorecoordination(Pd0.01),andVASscorewaslowering7、roupD(Pd0.05).ConclusionDexmedetomidineasasupplementtolocalanesthesiaforcervicalspinaloperationcaneffectivelyprovidebettersedationandreducepostoperativepainwithoutrespiratorydepression.[Keywords]Dexmedetomidine;Sedation;Cervicalspinaloperation[JiangsuMedJ,April208、14,40(7):825-827.]脊柱手术尤其颈椎手术可损伤脊髓或脊神经,吸抑制,颈椎后路手术要求患者采取俯卧位,一旦出虽然术中监测体感诱发电位及运动诱发电位可监测现呼吸系统不良反应无法及时抢救,故限制了常规神经损伤,但仍不能完全避免对神经和脊髓的误伤。镇静镇痛药的使用。右美托咪定是一种高选择性的为避免脊髓损伤,外
3、ncervicalspinaloperationbyposteriorapproachunderlocalanesthesiaD1GtJi,JIFuhai,YANGJianping.Department0fAnesthesiology,FirstAffiliatedHospital,SoochowUniversity,Suzhou215006,CHINA[Abstract]ObjectiveToevaluatetheefficiencyofdexmedetomidineforsedationduringcervicals
4、pinaloperationviaposteriorapproachunderlocalanesthesia.MethodsForty-twopatientswereequallyrandomizedintotwogroupsofD(receiveddexmedetomidine0.5g/kgfor10minasaloadingdose,fo1lowedbyacontinuousinfusionat0.3g·kg·min)andC(receivedequalvolumeofnormalsaline).Thechanges
5、ofMAP,HRandSpOzwererecordedonarrivalatoperatingroom(TO),beforeskinincision(T1),atskinincision(T2),in1hourafterincision(T3),in2hoursafterincision(T4)andatskinsuture(T5).RamsaysedationscaleofgroupDwasevaluatedandtheamountofantihypertensivedrugs,coordinationofthepat
6、ients,andVASpainscorein2hoursafteroperationweremeasured.ResultsThevaluesofMAPandHRatT1toT5wereloweringroupDthanthoseingroupC(P<0.05).ComparedwithgroupC,thepatientsrequiredlessantmypertensivetreatment(P<0.O1)andshowedmorecoordination(Pd0.01),andVASscorewaslowering
7、roupD(Pd0.05).ConclusionDexmedetomidineasasupplementtolocalanesthesiaforcervicalspinaloperationcaneffectivelyprovidebettersedationandreducepostoperativepainwithoutrespiratorydepression.[Keywords]Dexmedetomidine;Sedation;Cervicalspinaloperation[JiangsuMedJ,April20
8、14,40(7):825-827.]脊柱手术尤其颈椎手术可损伤脊髓或脊神经,吸抑制,颈椎后路手术要求患者采取俯卧位,一旦出虽然术中监测体感诱发电位及运动诱发电位可监测现呼吸系统不良反应无法及时抢救,故限制了常规神经损伤,但仍不能完全避免对神经和脊髓的误伤。镇静镇痛药的使用。右美托咪定是一种高选择性的为避免脊髓损伤,外
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