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时间:2020-05-02
《利多卡因雾化吸人在老年患者全身麻醉诱导中的应用.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·998·ShanghaiMedj,2012,Vo1.35,No.12●临床麻醉●利多卡因雾化吸入在老年患者全身麻醉诱导中的应用季惠尤新民程志军施关新【摘要】目的观察体积分数为0.02的利多卡因超声雾化吸入对老年患者全身麻醉诱导中血流动力学变化的影响。方法选择2011年9月一2012年2月于上海交通大学医学院附属新华医院崇明分院择期行中上腹部手术的老年患者6O例,美国麻醉医师学会(ASA)分级I或Ⅱ级,随机分为对照组、利多卡因静脉组(静脉组)和利多卡因超声雾化吸人组(吸人组),每组2O例。观察麻醉诱导前()、气管插管前(T。)以及气管插管后1m
2、in(T)、3min(T。)、5min(T)的收缩压(SBP)、舒张压(DBP)、心率(HR)和脉搏血氧饱和度(SOz)的变化。结果3组间的性别构成、年龄、体重及ASA分级构成的差异均无统计学意义(P值均2>0.05)。所有患者均在第1次操作获得气管插管成功。与同组T。时间点比较:3组在T时间点的SBP、DBP均显著降低(P值均3、T时间点的DBP亦显著升高(P值均d0.05);3组在T时间点、对照组在T。和T时问点的HR均显著升高(P值均d0.05)。与对照组同时间点比较:静脉组在T时间点的DBP显著升高(P<0.05),T时间点的SBP显著降低(P4、雾化吸人;老年;血流动力学ApplicationoflidocainenebulisedinhalationforgeneralanesthesiaintheelderlyJIHui,YOUXinmin,CHENGZhqun,SHIMeixin.DepartmentofAnesthesiology,ChongmingBranchofXinhuaHospital,ShanghaiJiaotongUniversitySchoolofMedicine,Shanghai202150,ChinaCorrespondingauthor:y0UXinmin.5、E-mail:babayouxinmin@hotmail.com[Abstract]ObjectiMeTOobservetheefectofultrasonicnebulizationof2%lidocaineonhemodynamicsduringgeneralanesthesiainelderlypatients.MethodsSixtyelderlypatients(AmericanSocietyofAnesthesioIogistsEASA3gradeIorⅡ)scheduledforepigastricsurgeryfromSepte6、mber2011toFebruary2012wererandomlydividedintocontrolgroup,lidocaineintravenousinjectiongroup,andultrasonicnebulizationgroup.Systolicbloodpressure(SBP),diastolicbloodpressure(DBP),heartrate(HR)andsaturationofbloodoxygen(SpO2)wererecordedbeforeanesthesiainduction(T0),beforeint7、ubation(T1),andat1min(T2),3mins(T3)and5mins(T4)afterintubation.ThewithfailedinwhominbubationatthefirsttimewereexcludedfrOmstatisticalanalysis.ResultsTherewerenosignificantdiferencesinage,gender,bodyweightorASAgradeamongthethreegroups(allP>0.05).Trachealintubationwassuccessfu8、llytakeninallthepatients.ComparedwiththoseatTo,SBPandDBPinthethreegroupsand
3、T时间点的DBP亦显著升高(P值均d0.05);3组在T时间点、对照组在T。和T时问点的HR均显著升高(P值均d0.05)。与对照组同时间点比较:静脉组在T时间点的DBP显著升高(P<0.05),T时间点的SBP显著降低(P4、雾化吸人;老年;血流动力学ApplicationoflidocainenebulisedinhalationforgeneralanesthesiaintheelderlyJIHui,YOUXinmin,CHENGZhqun,SHIMeixin.DepartmentofAnesthesiology,ChongmingBranchofXinhuaHospital,ShanghaiJiaotongUniversitySchoolofMedicine,Shanghai202150,ChinaCorrespondingauthor:y0UXinmin.5、E-mail:babayouxinmin@hotmail.com[Abstract]ObjectiMeTOobservetheefectofultrasonicnebulizationof2%lidocaineonhemodynamicsduringgeneralanesthesiainelderlypatients.MethodsSixtyelderlypatients(AmericanSocietyofAnesthesioIogistsEASA3gradeIorⅡ)scheduledforepigastricsurgeryfromSepte6、mber2011toFebruary2012wererandomlydividedintocontrolgroup,lidocaineintravenousinjectiongroup,andultrasonicnebulizationgroup.Systolicbloodpressure(SBP),diastolicbloodpressure(DBP),heartrate(HR)andsaturationofbloodoxygen(SpO2)wererecordedbeforeanesthesiainduction(T0),beforeint7、ubation(T1),andat1min(T2),3mins(T3)and5mins(T4)afterintubation.ThewithfailedinwhominbubationatthefirsttimewereexcludedfrOmstatisticalanalysis.ResultsTherewerenosignificantdiferencesinage,gender,bodyweightorASAgradeamongthethreegroups(allP>0.05).Trachealintubationwassuccessfu8、llytakeninallthepatients.ComparedwiththoseatTo,SBPandDBPinthethreegroupsand
4、雾化吸人;老年;血流动力学ApplicationoflidocainenebulisedinhalationforgeneralanesthesiaintheelderlyJIHui,YOUXinmin,CHENGZhqun,SHIMeixin.DepartmentofAnesthesiology,ChongmingBranchofXinhuaHospital,ShanghaiJiaotongUniversitySchoolofMedicine,Shanghai202150,ChinaCorrespondingauthor:y0UXinmin.
5、E-mail:babayouxinmin@hotmail.com[Abstract]ObjectiMeTOobservetheefectofultrasonicnebulizationof2%lidocaineonhemodynamicsduringgeneralanesthesiainelderlypatients.MethodsSixtyelderlypatients(AmericanSocietyofAnesthesioIogistsEASA3gradeIorⅡ)scheduledforepigastricsurgeryfromSepte
6、mber2011toFebruary2012wererandomlydividedintocontrolgroup,lidocaineintravenousinjectiongroup,andultrasonicnebulizationgroup.Systolicbloodpressure(SBP),diastolicbloodpressure(DBP),heartrate(HR)andsaturationofbloodoxygen(SpO2)wererecordedbeforeanesthesiainduction(T0),beforeint
7、ubation(T1),andat1min(T2),3mins(T3)and5mins(T4)afterintubation.ThewithfailedinwhominbubationatthefirsttimewereexcludedfrOmstatisticalanalysis.ResultsTherewerenosignificantdiferencesinage,gender,bodyweightorASAgradeamongthethreegroups(allP>0.05).Trachealintubationwassuccessfu
8、llytakeninallthepatients.ComparedwiththoseatTo,SBPandDBPinthethreegroupsand
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