吸烟对冠状动脉旁路移植术麻醉诱导期BIS的影响.pdf

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1、临床研究Linchuangyanjiu《中国医学创新》第11卷第3期(总第285期)2o14~1月吸烟对冠状动脉旁路移植术麻醉诱导期BIS的影响魏利娟①高文根①马亚飞①【摘要】目的：探讨吸烟对冠状动脉旁路移植术患者麻醉诱导期脑电双频指数(BIS)和血流动力学的影响。方法：选取40例行冠脉搭桥手术患者，ASAlI～Ⅲ级，按随机数字表法分为吸烟组20例和未吸烟组2O例。所有患者均使用咪唑安定、依托咪酯、异丙酚、舒芬太尼和维库溴铵进行麻醉诱导，记录插管前、插管即刻和插管后1、2、3rain的心率(HR)、平均

2、动脉压(MAP)和BIS值。结果：两组诱导前的基础MAP和BIS的比较差异无统计学意义(P>0．05)；吸烟组的基础HR慢于未吸烟组。吸烟组气管插管即刻和气管插管后1、2min的BIS值均高于未吸烟组(P<0．05)；与未吸烟组相比，吸烟组在气管插管即刻、插管后1、2minHR和MAP升高更明显(P

3、麻醉诱导；BISEfectsofSmokingonBispectralIndexinCoronaryArteryBypassGraftingPatientsduringInductionofAnesthesia／WEILi-juan，GAOWen—gen，MAYa—fei．／／MedicalInnovationofChina，2014，11(03)：030-032【Abstract】objective：Toobservetheefectsofsmokingonbispectralindex(BIS)an

4、dhemodynamicsincoronaryarterybypassgrafting(CABG)patientsduringinductionofanesthesia．Method：加patients(ASAII—m)forCABGweredividedintotwogroupsaccordingtorandomnumbertablemethod：smokers(n=20)andnon-smokers(n=20)．Allpatientswereusingmidazolam，etomidate，prop

5、ofol，sufentanilandvecuroniumforinductionofanesthesia．Heartrate(HR)，meanarterialpressure(MAP)andBISwererecordedatintubationimmediately，beforeintubation，1min，2minand3minafterintubation．Result：MAPandBISbeforethebasisofthetwogroupscomparisondiferenceshadnost

6、atisticalsignificance(P>O．05)；ThebasisofHRinthesmokinggroupwasslowerthanthenon-smokinggroup．Trachealintubationandtrachealintubationafter1，2min，BISvaluesofthesmokinggroupwerehigherthanthenon—smokinggroup(P<0．05)；Comparedwiththenon—smokinggroup，duringendot

7、rachealintubationandafterintubation1，2min，HRandMAPofthesmokinggroupwereincreasedmoresignificantly(P<0．05)．Conclusion：SmokingafectscoronaryarterybypassgraftinganesthesiainductionperiodoftheBIS，smokingpatientswithcoronaryarterybypassgraftsurgeryanesthesiai

8、nductionperiodhemodynamicchangeismoreintense，moreattentionshouldbepaidtomaintainhemodynamicstability，effectivepreventionofmyocardialischemia．IKeywords】Smoking；Coronaryarterybypassgrafting；Anesthesiainduetton；BISFirst-autho