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《七氟醚吸入不同时间对患儿顺式阿曲库铵肌松效应的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、七氟醚吸人不同时间对患儿顺式阿曲库铵肌松效应的影响许斌兵,柏林。,徐颖2谭延哲。,叶茂。(1.遂宁市中心医院麻醉科,四川遂宁629000;2.重庆医科大学附属儿童医院麻醉科,重庆400014)中图分类号R971+.2;R969文献标志码A文章编号1001—0408(2012)22—2065—03DOI10.6039/j.issn.1001·0408.2012.22.17摘要目的:探讨七氟醚吸入时间对患儿顺式阿曲库铵肌松效应的影响。方法:择期行颜面、颈部手术(唇裂修复术、腭裂修复术和甲舌囊肿切除术)的患儿6O例,美国麻醉师协会(ASA)分级I或Ⅱ级,年龄2
2、48岁,按用药情况分为吸入七氟醚30min组(S。组)、吸入七氟醚60rain组(s。。组)和全凭静脉麻醉组(T组),各20例。麻醉诱导后,静脉注射顺式阿曲库铵0.15mg·kg,s组和s组插管后即刻吸入七氟醚,维持呼气末浓度2.5%,分别吸入30rain和60min;T组全凭静脉麻醉。行连续4个成串刺激(TOF)方式,采用肌松监测仪监测拇内收肌的肌松情况。记录肌松起效时间(To)、最大效应持续时间(DUR。)、临床作用时间(DUlL)、恢复指数(RI)、体内作用时间(DUR,)及TOFR(T/T。)恢复至90%的时间(TOFR)。结果:3组L比较差异无
3、统计学意义(JP>0.05);与T组比较,S组和Se。组DUR。、DU、TOFR延长,S。组DUR、RI延长(尸<0.05);与S。。组比较,S组DUR。、DU&、DuR和TOFR延长(P4、ectOfCisatracuri.aminChildrenXUBin—bing(Dept.ofAnesthesiology,SuiningMunicipalCentralHospital,SichuanSuining629000,China)BAILin,XUYing,TANYan—zhe,YEMao(Dept.ofAnesthesiology,Children’sHospitalofChongqingMedicalUniversity,Chongqing400014,China)ABSTRACT0BJECTIVE:Toinvestigatetheinf5、luenceofdifferentdurationofsevofluraneinhalationonmusclerelaxationeflfectofcisatracuriuminchildren.METH0DS:60children(2~8yearsold.ASAI~Ⅱ)undergoingelectivefacialandnecksurgery(cheiloplasty,palatorrhaphyandthyroglossalductcystexcision)weredividedinto30一minsevofluraneinhalationgrou6、p(group$30),6O—rainsevofluraneinhalationgroup(groupS~0)andtotalintravenousanesthesiagroup(groupT)with20childrenineachgroup,accordingtodruguse.Afteranesthesia,theyweregivenintravenousinjectionofcisatracurium0.15mg·一,andgroupS3oandS∞wereexposedto2.5%sevofluraneaftertrachealintubati7、onfor30rainand6OrainwhilegroupTreceivedtotaljntravenousanesthesia.Thosegroupsreceivedatrain—of-four(TOF)mode.andmusclerelaxationmonitorwasusedtomonitorthemusclerelax—ation.Onsettime(To),durationofpeakefect(DUR。),recoveryindex(RI),durationofclinica1action(DU凡),durationoftota1actio8、n(DUR)andtimetoTOFR(T4/T1)90%(TOFRo9)wer
4、ectOfCisatracuri.aminChildrenXUBin—bing(Dept.ofAnesthesiology,SuiningMunicipalCentralHospital,SichuanSuining629000,China)BAILin,XUYing,TANYan—zhe,YEMao(Dept.ofAnesthesiology,Children’sHospitalofChongqingMedicalUniversity,Chongqing400014,China)ABSTRACT0BJECTIVE:Toinvestigatetheinf
5、luenceofdifferentdurationofsevofluraneinhalationonmusclerelaxationeflfectofcisatracuriuminchildren.METH0DS:60children(2~8yearsold.ASAI~Ⅱ)undergoingelectivefacialandnecksurgery(cheiloplasty,palatorrhaphyandthyroglossalductcystexcision)weredividedinto30一minsevofluraneinhalationgrou
6、p(group$30),6O—rainsevofluraneinhalationgroup(groupS~0)andtotalintravenousanesthesiagroup(groupT)with20childrenineachgroup,accordingtodruguse.Afteranesthesia,theyweregivenintravenousinjectionofcisatracurium0.15mg·一,andgroupS3oandS∞wereexposedto2.5%sevofluraneaftertrachealintubati
7、onfor30rainand6OrainwhilegroupTreceivedtotaljntravenousanesthesia.Thosegroupsreceivedatrain—of-four(TOF)mode.andmusclerelaxationmonitorwasusedtomonitorthemusclerelax—ation.Onsettime(To),durationofpeakefect(DUR。),recoveryindex(RI),durationofclinica1action(DU凡),durationoftota1actio
8、n(DUR)andtimetoTOFR(T4/T1)90%(TOFRo9)wer
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