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时间:2020-05-02
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1、·1502·逝临床医学2014年9)q第16卷第9期2GnecchiM,HeH,NoiseuxN,eta1.Evidencesupportingparacrinebhnd,placebo—controled,dose—escalationstudyofintravenousadulthypothesisforAkt——modifiedmesenchymalstemcell——mediatedcardiachunzanmeseuchymalstemcells(prochyma1)afteracutemyocardialprotectionandf
2、unctionalimprovement.TheFASEBJourml,2006,infarction.JournaloftheAmericanColegeofCardiology,20(19,54(24):2O(6):661~669.2277-2286.3NakanishiC,Yan~ishiM,YamaharaK,eta1.Activationofc~diac10TrachtenbergB,VehzquezDL,WilliamsAR,etalRationaleandprogenitorceilsthroughparacrineefectso
3、fmesenchymalstemcels.designoftheTramendocardialInjectionofAutologousHumanCeltsBiochemicalandbiophysicalresearchcommunications,2008,374(1):11~16.bonemalTowormesenchyma1)inChronicIschemicLeftVentricular4SilvaGV,LitovskyS,AssadJAR,eta1.MesenchymalstemcellsDysfunctionandHeartFai
4、lureSecondarytoMyocardialInfarction(TAC—differentiateintoanendothelialphenotype,enhartcevasculardensity,andHFT)trial:arandomized,double—bhnd,placebo—controledstuayofsafetyimproveheartfunctioninacaninechronicischerniamode1.Circulation,andeficacy.Americanheartjournal,2011,161(
5、3):487-493.2005,111(2):150~156.11JanssensS,DuboisC,BogaertJ,eta1.Autologousbonemarrow—5ErbsS,LinkeA,SchachingerV,eta1.RestorationofMicrovascularderivedstem——celtransferinpatientswithST——segmentelevationFunctionintheInfarct—RelatedArterybylntracoronaryTransplantationmyocardia
6、linfarction:double—bhnd,randomisedcontrolledtrialTheofBoneMarrowProgenitorCellsinPatientsWithAcuteMyocardialLancet,2006,367(9505):113~121InfarctionTheDopplerSubstudyoftheReinfusionofEnriched12LundeK,SolheimS,AakhusS,etalIntracoronaryinjectionofProgenitorCellsandInfarctRemode
7、linginAcuteMyocardialInfarctionmononuclearbonemarrowcellsinacutemyocardialinfarctionNew(REPAIR—AM1)Tria1.Circulation,2007,116(4):366~374.En~andJournalofMedicine,2006,355(12):1199~1209.6BeltramiAP,BaducchiL,TorelaD,etalAdultcardiacstemcellsare13HitchA,NijveldtR,vanderVleutenP
8、A,eta1.IntracoronaryinfusionmultipotentandsupportmyocardiMregeneration.Cel,
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