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《单肺通气对七氟醚吸入麻醉肺摄取的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、2014年3月第35卷第3期IntJAnesthResus,Marc—h2—014—,Vo1.3—5,No.3213·论著·单肺通气对七氟醚吸入麻醉肺摄取的影响王伟芝罗艳华董桂敏王绍明【摘要】目的观察吸入麻醉过程中单肺通气(one-lungventilation,OLV)与双肺通气(two-lungventilation,TLV)比较七氟醚的肺摄取情况。方法选择食道癌根治术患者15例(OLV组)和胃癌根治术患者15例(TLV组),分别于全麻诱导后插入双腔支气管导管或单腔气管导管控制呼吸,行七氟醚吸入麻醉,记
2、录每组患者各个时点的脑电双频指数(bispectralindex,BIS)、七氟醚吸入气浓度(Fi)和呼出气浓度(Et),并计算Et/Fi,进行组间及组内各时间点的比较。结果组间:OLV组BIS高于TLv组(P<0.05);OLV组Et/Fi高于TLV组(P<0.01oOLV组:BIS呈逐渐下降趋势,5min达到临床麻醉水平(60),5minN120min维持在临床麻醉深度(4060);Et呈逐渐上升趋势,2min一30min未进入稳态(P3、~50min内未进入稳态(P<0.05),50min达到稳态(连续30min)(P>0.05),50min~120min变化无统计学意义(P>0.05)。TLv组:BIS呈逐渐下降趋势,2min达到临床麻醉水平(60),2min~70min维持在临床麻醉深度(40~60),70min~120min低于40;Et呈逐渐上升趋势,2min~20min未进入稳态(P<0.05),20min达到稳态(连续30min)(P>0.05)。Et/Fi呈逐渐升高趋势,2min达到稳态,2min120min变化无统计学意义(4、尸>0.05o结论OLV对七氟醚的肺摄取有一定影响。OLV摄取总量少于TLv,2min~50min摄取速率高于TLv。OLV与TLV均可达到满足手术要求的麻醉深度,但TLV组在70min后应适当调整吸入浓度以避免麻醉过深。与TLv比较,OLV麻醉深度较浅,达到稳定麻醉状态的时间较长。【关键词】单肺通气;七氟醚;肺摄取;脑电双频指数;呼出气浓度Efectofone4ungventilationonpulmonaryuptakeofsevofluraneWangWeizhi,LuoYanhua,DongGuim5、in,WangShaoming.DepartmentofAnesthesiology,WeifangPeopleHospital,Weifang261041,ChinaCorrespondingauthor:LuoYanhua,Emoil:littlebird20053168@aliyun.con【Abstract】ObjectiveToobservetheeffectofone-lungventilation(OLV)ortwo-lungventilation(TLV)onpulmonaryuptakeo6、fsevoflurane.MethodsFifteenpatientswithesophagealtumoreetomyandfifteenpatientswithstomachtumoreetomywereselectedforOLVandTLVduringtheoperation.respectively.Sevofluranewasusedforthegeneralanesthesia.Bispectralindex(BIS),FiandEtwererecordedateachmeasurementp7、oint,andEt/Fiwascalculated.ResultsTheBISvalueofOLVgroupwashigherthanthatofTLVgroup(P<0.05),Et/FiinOLVgroupwashigherthanTIJVgroup(P<0.O1).OLVgroup:theBISvaluegraduallydecreasedandreachedintoananestheticstate(BIS:60)at5rain,andthenenoughanesthesiadepth(BIS:48、0-60)wasmaintainedduring5min一120min.Etgraduallyincreasedandreachedintoasteadystateat30min.EfFiincreasedandreachedintoasteadystateat50minandtheEt/Fiduring50min一120minhadnostatisticalsignificance(P>0.05).TLVgro
3、~50min内未进入稳态(P<0.05),50min达到稳态(连续30min)(P>0.05),50min~120min变化无统计学意义(P>0.05)。TLv组:BIS呈逐渐下降趋势,2min达到临床麻醉水平(60),2min~70min维持在临床麻醉深度(40~60),70min~120min低于40;Et呈逐渐上升趋势,2min~20min未进入稳态(P<0.05),20min达到稳态(连续30min)(P>0.05)。Et/Fi呈逐渐升高趋势,2min达到稳态,2min120min变化无统计学意义(
4、尸>0.05o结论OLV对七氟醚的肺摄取有一定影响。OLV摄取总量少于TLv,2min~50min摄取速率高于TLv。OLV与TLV均可达到满足手术要求的麻醉深度,但TLV组在70min后应适当调整吸入浓度以避免麻醉过深。与TLv比较,OLV麻醉深度较浅,达到稳定麻醉状态的时间较长。【关键词】单肺通气;七氟醚;肺摄取;脑电双频指数;呼出气浓度Efectofone4ungventilationonpulmonaryuptakeofsevofluraneWangWeizhi,LuoYanhua,DongGuim
5、in,WangShaoming.DepartmentofAnesthesiology,WeifangPeopleHospital,Weifang261041,ChinaCorrespondingauthor:LuoYanhua,Emoil:littlebird20053168@aliyun.con【Abstract】ObjectiveToobservetheeffectofone-lungventilation(OLV)ortwo-lungventilation(TLV)onpulmonaryuptakeo
6、fsevoflurane.MethodsFifteenpatientswithesophagealtumoreetomyandfifteenpatientswithstomachtumoreetomywereselectedforOLVandTLVduringtheoperation.respectively.Sevofluranewasusedforthegeneralanesthesia.Bispectralindex(BIS),FiandEtwererecordedateachmeasurementp
7、oint,andEt/Fiwascalculated.ResultsTheBISvalueofOLVgroupwashigherthanthatofTLVgroup(P<0.05),Et/FiinOLVgroupwashigherthanTIJVgroup(P<0.O1).OLVgroup:theBISvaluegraduallydecreasedandreachedintoananestheticstate(BIS:60)at5rain,andthenenoughanesthesiadepth(BIS:4
8、0-60)wasmaintainedduring5min一120min.Etgraduallyincreasedandreachedintoasteadystateat30min.EfFiincreasedandreachedintoasteadystateat50minandtheEt/Fiduring50min一120minhadnostatisticalsignificance(P>0.05).TLVgro
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