不同剂量瑞芬太尼对全麻诱导期气管插管血流动力学的影响.pdf

《不同剂量瑞芬太尼对全麻诱导期气管插管血流动力学的影响.pdf》由会员上传分享，免费在线阅读，更多相关内容在行业资料-天天文库。

1、一1674一ChinJLabDiagn，Septemher，2013，Vol17，No．9文章编号：1007—4287(2013)09—1674—04不同剂量瑞芬太尼对全麻诱导期气管插管血流动力学的影响李仔男，孙岩，刘岩(吉林大学中日联谊医院麻醉科，吉林长春130021)摘要：目的观察复合异丙酚下不同剂量瑞芬太尼对全麻诱导期气管插管时血流动力学的影响，探索瑞芬太尼全麻诱导期气管插管的较佳剂量。方法将6O例患者随机分为4组，对照组诱导给予芬太尼，其它3组诱导给予不同剂量的瑞芬太尼，其余诱导药物一致，待患者意识消失后，行气管内插管。观察从入室到插管后5分钟之内的HR、SBP、DBP、M

2、AP。结果瑞1组SBP、MAP值在插管后1min、2rain时均有较大的升高，与其余3组组间相比差异有统计学意义(Pg／kg对比，1．5>g／kg剂量诱导可以很好的抑制插管后心血管应激反应。关键词：瑞芬太尼；气管插管；应激反应中图分类号：R971．2文献标识码：AEffectsofdifferentdosesremifentanilonhemodynamicrespons

3、estotrachealintubationLIZi—nan，SUNYah，LIUYah．(DepartmentofA72PsAesi0Zog，China-JapanUnionHospitalDJilinUniversity，Changchun130021，China)Abstract：ObjectiveToinvestigatetheeffectofdifferentdoseremifentanilcombinedwithpropofolOntracheaintu—bationhemodynamiechangesduringinductionofgeneralanesthesia

4、，andtOoptimizeabetterdosageofremifentanildur—ingthisphase．MethodsSixtyASAphysicalstatusI一Ⅱpatients，undergoingmajorsurgery，wererandomlyassignedtO4groups．andthenthecomparedgroupadministerfentanil，theothergroupsadministerdifferentdoseofremifentanil，thetracheawasintubated60safterthemedicineinfusio

5、n．Intubationconditionandhemodynamicchangesintra—cheslintubationwereobserved．NoteHR、SBP、DBP、MAPinthetimeofafterthepatientsintheoperatingroom，in—duction，afterintubationin5min．ResultsAfterintubation1min，2min，SBP、MAPofR1groupwerelargelyin—cEeased，andcomparedwiththeother3groupsthedifferencebetweeng

6、roupswasstatisticallysignificant(P％0．05)；InR2andR3groups，thebloodpressurebegantoriseimmediatelyfromthetubeinserted，stillbelowthelevelbeforeanesthesia，andbloodpressurerisesteadilyinR2group，comparedbetweenwithT3，T4，T5，T6wasnosignificantdifference．ConclusionSingleadministeredintravenousdosage1t~g

7、／kgofremifentanilcannoteffectivelyinhibitcardi—ovascularresponses．ComparedRemifentanil2．0t~g／kggroup，thedosage1．5gg／kgandsingleintravenousdosecaninducegoodcardiovascularstressresponseafterintubation．Thedosage1．5t*g／kgisidealdoseduringtr