卵圆孔未闭经导管封堵术的临床疗效和安全性评价_杨延坤

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1、心血管外科杂志(电子版)2014年12月第3卷第4期JournalOfCardiovascularSurgery(ElectronicEdition)，December，2014，Vol．3，No．4·177··临床研究·卵圆孔未闭经导管封堵术的临床疗效和安全性评价杨延坤郑宏蒋世良徐仲英赵世华张戈军李世国金敬琳兰天杨帆【摘要】目的探讨经导管卵圆孔未闭(PFO)封堵术的临床疗效，并对其安全性进行评价。方法回顾2010年2月至2014年5月于我院行PFO封堵术35例，收集临床资料并对所有患者进行随访。结果封

2、堵成功31例(88.6%)，其中合并不明原因脑卒中史26例(有1例同时合并偏头痛发作)，合并单纯先兆性偏头痛者3例，合并短暂性脑缺血发作(TIA)2例，所有患者术后均无脑梗死病史，3例先兆型偏头痛者中2例术后6个月头痛消失，1例明显减轻，2例TIA中1例术后无再发，1例术后3个月内发作3次，之后无再发。结论PFO经导管封堵术对不明原因的脑卒中和先兆性偏头痛的二级预防是一项安全有效的技术，但仍需要严格把握介入治疗的适应证。［关键词］卵圆孔，未闭;卒中;偏头痛;封堵术［中图分类号］Ｒ654.22［文献标识码

3、］A［文章编号］2095-2260(2014)04-0007-04AssessmentoftheclinicaleffectsandsafetyoftranscatheterpatentforamenovaleocclusionYANGYan-kun，ZHENGHong，JIANGShi-liang，XUZhong-ying，ZHAOShi-hua，ZHANGGe-jun，LIShi-guo，JINJing-lin，LANTian，YANGFan．DepartmentofCardiology，Cardi

4、ovascularInstituteandFuwaiHospital，ChineseAcademyofMedicalSciencesandPekingUnionMedicalCollege，Beijing100037，ChinaCorrespondingauthor:ZHENGHong，Email:zheng_hung@126．com【Abstract】ObjectiveToexploretheclinicaleffectsandsafetyoftranscatheterclosureofpatentf

5、oramenovale(PFO)．MethodsPatientsadmittedtoauthor'shospitaltoreceivetranscatheterclosureofPFOwereenrolledretrospectivelyduringtheperiodfromFebruary2010toMay2014，clinicaldatawerecollectedandfollow-upinformationwasobtainedthroughtelephoneoratout-patientclin

6、icalinterview．ＲesultsAtotalof35patientswereenrolled，successfulocclusionofPFOwereobtainedin31patients(88.6%)，including26patientswithcryptogenicstroke，1ofwhichwasaccompaniedmigraine，3patientsweremigrainewithaura，2patientswithtransientischemicattack(TIA)，in

7、nopatientstherewasstrokeoccurredafterocclusion．Twopatientsaccompaniedmigrainewithauraresolvedafter6months，attacksdecreasedobviouslyin1patientwithmigraine．TIArecurrencedecreasedto3timesinthefirst3monthsin1patientsthennoTIAeventsreoccurred，1patientwithnoTI

8、Areoccurredafterocclusion．ConclusionsItiseffectiveandsafetyoftranscatheterclosureofPFOforsecondarypreventionofcryptogenicstrokeandmigrainewithaura，whilethereisstillneedtostrictlymanagementofPFOinterventioncriterion．【Keywor