功能性消化不良体表胃电图变化及多番立酮对其疗效评价

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1、第l2卷笫8蚜20／2年4月盅景景v04l_plr!20N0o28功能性消化不良体表胃电图变化及多番立酮对其疗效评价济南军臣总医院消化科(济青250031)张修礼权启镇陈桂荣孙自勤王要军江学良李文波尚瑞莲目的：观察功能性消化不良(FD)患者空腹体表胃电囤变亿，同时观察多番立酮对其疗效的评价。方法：50倒具有上腹隐痛、腹胀、暖气、呕吐等疰状，但电子胃镜厦肝胆胰B超检查均未发现阳性病变者，诊断为FD。多番立酮，10mg／；~，3收／d共2周。所有病^于治疗前后均进行胃电囤描记，井进行比较分析。结果：74％(37／50)的FD惠者空腹体表胃电囤异常，表现

2、为过速或过缓服用多番立酮后36倒FD惠者(72％，36／50)临床症状麓得改善。同时其隹表空疆胃电圈正常化率办明里提高(70％VS26％P

3、”，SunZiqin，alGeneralHospitalofJinanMilitaryArea，Jinan，ShandongProvince，250031．AbstractObjective：Toinvestigatethecutaneouselectrog&strograpb(EGG)inthepa*ienrswithfunctionaldyspepsia(FD)andevaluatethetherapeuticefficacyofdomperidoneonFDMethods：Patiemswithpostprandialab—dominaIpa

4、inbelchvomirtingands00n，wcreenrolled“)ourobservationtria1．ThediagnosisofFDWaSobtainedwhennopoNrivetindings~,crcavailableafzerthegasrroendoscopyandaonographexamina*ionofliverandpancreas．Domperidonewasgivenorallyin1hepatientswilhFDatthedose0f1Omg，threetimesdailyAfterr,voweeb。frh

5、erap5。，theclinicalmanifesratior~s~MereevaluatedThefastingeu{aneotlselecrrogastrographwasanalyzedbeforeandafterthetreatment．Results：TheabnormalityoffastingcuIaneou5clectrogas*rographisvery~on]nloninthepatientswithFD(74％，37／50)Tachygastriaorbradygasrria~vcrepresentinthepatientsw

6、ithgastricdysrhythmiasTheclinicalsymprorm~，such3spostprandialabdominalpai~l，belch，vomittingerc~A,crCalleviatedordisappearedinourdinicaltrial(72％，36／50)．Atthe~lltI2etimethenormalizationoffastinggutaneoll8eIec*rogastrographim—provedsignificantlyafterthetherapy(70％VS26％P<005)．Con

7、clusions：GastricdysrhythmiasislikelytOberesponsiblefortheclinicalsymptomsinpatientswithFDDompefidoneistheeffectivedrugintreatment0fFD，anditcanimprovethenormalization。ftheEGGinpatientswithFD．Keywords：FunctionalDyspepsia(FD)；Domperidone；Electrogasrrograph(EGG)功能性消化不良(functionald

8、yspepsia，FD)是消表胃电图的影响和临床疗效进行了观察。化科疾病中的常见病，其病固尚未完全阐明，但胃肠l临床资料及