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《低频脉冲超声干预膝骨关节炎模型兔关节软骨及滑膜水通道蛋白3的表达_唐进》由会员上传分享，免费在线阅读，更多相关内容在行业资料-天天文库。
1、中国组织工程研究与临床康复第15卷第11期2011–03–12出版JournalofClinicalRehabilitativeTissueEngineeringResearchMarch12,2011Vol.15,No.11低频脉冲超声干预膝骨关节炎模型兔关节软骨及滑膜水通道蛋白3的表达★唐进，黄良库，彭李华，李东，陈世荣Effectoflow-frequencypulsedultrasoundonexpressionofarticularcartilageandsynovialaquaporin3inrabbitkneeosteoarthriticmodel
2、sTangJin,HuangLiang-ku,PengLi-hua,LiDong,ChenShi-rongAbstractBACKGROUND:Previousstudiesdemonstratedthat,low-frequencypulsedultrasoundcanpromoterepairoffull-thicknessDepartmentofOrthopedics,thearticularcartilagedefects,delaytheprogressionofkneeosteoarthritis.Aquaporin3existsonarticula
3、rcartilageandsynovialSecondAffiliatedmembrane,whichplaysanimportantroleinosteoarthritis.HospitalofOBJECTIVE:Toobservetheeffectoflow-frequencypulsedultrasoundontheexpressionofarticularcartilageandsynovialChongqingMedicalaquaporin3inrabbitswithkneeosteoarthritis.University,Chongqing400
4、016,METHODS:ExperimentalosteoarthritiswasreplicatedinkneesofmatureNewZealandrabbitsbyfixingtheirleftbackkneesChinastraightenedlyinplastercast.TheexperimentalanimalsreceivedIFPUStherapy,ofwhichtheintensitywas2.0W,andthefrequencywas1MHz.TheIFPUStherapywasadministeredonceadayandlastedfo
5、r15minuteseverytime.ForthecontrolTangJin★,Studyinggroup,shamUStherapywasadministered.Theimmunohistochemistrywasusedtodetecttheexpressionofarticularcartilageformaster’sdegree,Physician,andsynovialaquaporin3at2,4and8weeksaftertherapy.DepartmentofRESULTSANDCONCLUSION:Withthemodelingtime
6、prolonged,theexpressionofarticularcartilageandsynovialaquaporin3Orthopedics,theineachgroupwereincreased.Comparedwiththecontrolgroup,theexpressionofarticularcartilageandsynovialaquaporin3SecondAffiliatedwaslowerintheexperimentalgroup(P<0.01).Itissuggestedthatthelow-frequencypulsedultr
7、asoundmightreducetheHospitalofChongqingMedicalexpressionofaquaporin3inarticularcartilageandsynovialatproteinleve1,relievejointswelling,reducetheseverityofarticularUniversity,cartilageandsynoviumdegeneration,andhaveaprotectiveeffectoncartilageandsynovialmembrane.Chongqing400016,ChinaT
8、angJ,HuangLK
