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1、中国组织工程研究与临床康复第15卷第4期2011–01–22出版JournalofClinicalRehabilitativeTissueEngineeringResearchJanuary22,2011Vol.15,No.4人工关节无菌性松动的早期诊断12魏慧，田京Earlydiagnosisofartificialjointasepticloosening12WeiHui,TianJingAbstractBACKGROUND:Themostsignificantfactorthataffectsthelifespanofjointprost
2、hesisistheartificialjointasepticloosening.DepartmentofOrthopaedics,OBJECTIVE:Toexploretheearlydiagnosisofartificialjointasepticlooseningmethodsinordertofacilitateactiveearlytreatment.ZhujiangHospital,METHODS:Acomputer-basedonlinesearchofPubMeddatabase,CNKIdatabase,VIPdatabas
3、eandWanfangdatabaseSouthernMedicalbetweenMay1997andOctober2010wasperformedtosearchrelatedarticleswiththekeywordsof“asepticloosening,artificialUniversity,Guangzhoujoint,prosthesis,osteolysis,earlydiagnosis”inEnglishorChinese.Literaturesrelatedtoasepticlooseningofprosthesiswer
4、e510282,Guangdongselected;inthesamefield,thearticlespublishedlatelyinauthoritativejournalswerepreferred.Atotalof182literatureswereProvince,Chinaprimarilyselected,and39documentsofwhichaddressingtheanalysisandtreatmentofasepticlooseningofprosthesiswereWeiHui,Departmentinvolved
5、forsummaryaccordingtoinclusioncriteria.ofOrthopaedics,RESULTSANDCONCLUSION:AsepticlooseningofprosthesisandosteolysishasacloserelationshipwithabnormalityofboneZhujiangHospital,SouthernMedicalmetabolismandinflammatoryreaction.Therefore,relatedcytokinesofinflammatoryreactionind
6、ucedbybonemetabolicmarkersUniversity,Guangzhouandwearparticlescanbeusedforearlydiagnosis.Isotopictracercannotonlydisplaysthemorphologyoftissueandorgan,but510282,Guangdongalsoreflectsthefunctionoftissuesandorgansbyshowingphysiologicalandbiochemicalprocessesoforgansortissues.P
7、rovince,Chinaweihuijunyi2007@Pathologicalchangescanbefoundearlierthanimagingforafewweeksorevenmonths.163.comWeiH,TianJ.Earlydiagnosisofartificialjointasepticloosening.ZhongguoZuzhiGongchengYanjiuyuLinchuangKangfu.Correspondenceto:TianJing,Master,2011;15(4):709-713.[http://ww
8、w.crter.cnhttp://en.zglckf.com]Associatechiefphysician,Professor,Department
