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页数:6页
时间:2017-12-10
《102例克罗恩病蒙特利尔分型分析》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、万方数据生堡塑丝盘查!!!!堡!旦笙丝鲞笙!塑堡垒堕』婴g!垒!墅壁!垫!!!!!!:垫!堕!:1102例克罗恩病蒙特利尔分型分析史济华陆星华【摘要】目的分析我国克罗恩病(CD)患者的蒙特利尔分型、治疗及预后特点,判断临床分型与抗酿酒酵母抗体(AsCA)、治疗方式和预后之间是否存在一定的关系。方法按照蒙特利尔分型对102例CD患者进行临床分型,并记录ASCA、肠道外表现、治疗方式和随诊情况。比较各亚型之间的差异。结果我国cD患者以A2亚型(52。9%)为主,回结肠受累(40,2%)和狭窄型病变(53。9%)多见,并发症的发生率与病程长短有关(P2、,肠瘘与疾病部位有一定关系(P=O.074),B1亚型疾病进展率高于B2亚型(P=o.018),B3亚型手术率最高(P=O.002)。As(=A阳性者占40.O%,ASCA阳性与病变部位、疾病行为、病情进展及治疗方式等无关(P>o.05)。结论cD患者的疾病行为随病程延长发生进展,并发症发生率及手术率上升,发生穿透性病变是手术治疗的首要原因。蒙特利尔分型可有助于判断是否需要手术治疗以及疾病的预后。【关键词l克罗恩病;蒙特利尔分型;抗酿酒酵母抗体;预后Thea岫lysisofMontr蛆IcIassj6∞tionfor102patientswithCrohn3、’sdi靶a靶SHJ.,i一^“口,LUXi"g—IIl“口.DPp口r£mP刀fo,G口盯,口P行抬r0ZD耳y,P放i行gU挖io刀MPdif口fCDZ£PgPH05pifnZ,C^i咒Ps£AcndP优yD厂Medic口fsciettce.Bcijing1QO’30,ChinaCDr阳s户。以d伽耳口越抽Dr:LUXi以g一^l‘l口,Em口iZ:Zz^巧2000@多Ⅱ^oD.co优.c刀.【Abn憎ct】0协ective1banalysisthefeaturesofIⅥontrealclassification,semm眦rkers,treatme4、ntandprognosisofChinesepalients耐thcrohn’sdisease(CD),∞dtoeStimatetherelationshipsbetweencJinidclassificationandaIlt卜sarcchammycescere访siaeantibody(ASCA),treatnlentandprOgnosis.M刮l-0凼Aretrospectivestudyof102consecutivedefirIiteCDcases、Ⅳereperfomedandallsubjectswe陀cIassifiedint0subt5、)rpesaccordingtoMontrealclassificatiorLTheresultsofAscA,extra_intestinalnlanifestatjon,treatm∞taJlddisea靶be}lavioratfollo忡upwerere00rdedand∞mpared蜘ongdifferentsubtypes.R荡山bTheA2subtype(52.9%)啪sdornillatedinChineseCDpatients.Ileocolonlocation(40.2%)andst^cturelesioll(53.9%)、^,erec(6、如【lITlofLThecomplicationratewasdepend肌tondiseasecourse(P0.05).测吣io璐Cmhn’sd7、iseaseⅡminJyattackyoungpeople、jI,ith砌epredoITli眦腿EarlroTlSetCDpatients11a”}ligherAs(二Apositiveratea11ddi$easeprogressivera记Thediseasebeha、,iorprogressesasS0lciated、Ⅳithdisease∞ur辩,andtherateofcomplicationandtheincreaseofsurgery.Thepenetratingbeha访oristhenuincau鸵forsurgery.Montr朗lc8、lassificationisu鸵fultopredictthed
2、,肠瘘与疾病部位有一定关系(P=O.074),B1亚型疾病进展率高于B2亚型(P=o.018),B3亚型手术率最高(P=O.002)。As(=A阳性者占40.O%,ASCA阳性与病变部位、疾病行为、病情进展及治疗方式等无关(P>o.05)。结论cD患者的疾病行为随病程延长发生进展,并发症发生率及手术率上升,发生穿透性病变是手术治疗的首要原因。蒙特利尔分型可有助于判断是否需要手术治疗以及疾病的预后。【关键词l克罗恩病;蒙特利尔分型;抗酿酒酵母抗体;预后Thea岫lysisofMontr蛆IcIassj6∞tionfor102patientswithCrohn
3、’sdi靶a靶SHJ.,i一^“口,LUXi"g—IIl“口.DPp口r£mP刀fo,G口盯,口P行抬r0ZD耳y,P放i行gU挖io刀MPdif口fCDZ£PgPH05pifnZ,C^i咒Ps£AcndP优yD厂Medic口fsciettce.Bcijing1QO’30,ChinaCDr阳s户。以d伽耳口越抽Dr:LUXi以g一^l‘l口,Em口iZ:Zz^巧2000@多Ⅱ^oD.co优.c刀.【Abn憎ct】0协ective1banalysisthefeaturesofIⅥontrealclassification,semm眦rkers,treatme
4、ntandprognosisofChinesepalients耐thcrohn’sdisease(CD),∞dtoeStimatetherelationshipsbetweencJinidclassificationandaIlt卜sarcchammycescere访siaeantibody(ASCA),treatnlentandprOgnosis.M刮l-0凼Aretrospectivestudyof102consecutivedefirIiteCDcases、Ⅳereperfomedandallsubjectswe陀cIassifiedint0subt
5、)rpesaccordingtoMontrealclassificatiorLTheresultsofAscA,extra_intestinalnlanifestatjon,treatm∞taJlddisea靶be}lavioratfollo忡upwerere00rdedand∞mpared蜘ongdifferentsubtypes.R荡山bTheA2subtype(52.9%)啪sdornillatedinChineseCDpatients.Ileocolonlocation(40.2%)andst^cturelesioll(53.9%)、^,erec(
6、如【lITlofLThecomplicationratewasdepend肌tondiseasecourse(P0.05).测吣io璐Cmhn’sd
7、iseaseⅡminJyattackyoungpeople、jI,ith砌epredoITli眦腿EarlroTlSetCDpatients11a”}ligherAs(二Apositiveratea11ddi$easeprogressivera记Thediseasebeha、,iorprogressesasS0lciated、Ⅳithdisease∞ur辩,andtherateofcomplicationandtheincreaseofsurgery.Thepenetratingbeha访oristhenuincau鸵forsurgery.Montr朗lc
8、lassificationisu鸵fultopredictthed
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