双歧杆菌四联活菌片治疗轮状病毒性肠炎患儿的疗效及对血清细胞因子的影响-论文.pdf

《双歧杆菌四联活菌片治疗轮状病毒性肠炎患儿的疗效及对血清细胞因子的影响-论文.pdf》由会员上传分享，免费在线阅读，更多相关内容在行业资料-天天文库。

1、药物与临床·中国现代医生2014年1月第52卷第2期双歧杆菌四联活茵片治疗轮状病毒性肠炎患儿的疗效及对血清细胞因子的影响何旒胡文辉1．浙江省浦江县中医院儿科，浙江浦江322200；2．浙江省台州市恩泽医疗中心(集团)台州医院儿内科，浙江临海317000【摘要】目的探讨双歧杆菌四联活菌片治疗轮状病毒性肠炎患儿的疗效及对血清细胞因子的影响。方法选择轮状病毒性肠炎患儿68例，分为观察组和对照组各34例。对照组患儿单纯予以调整饮食、抗病毒、补液、纠正水电解质紊乱及酸碱失衡等治疗。观察组在对照组治疗上加用双歧杆菌四联活菌片治疗

2、。结果观察组患儿的发热、呕吐及止泻时间明显短于对照组(P<0．05)。治疗3d后，观察组患儿的临床疗效明显高于对照组(x=4．66，P<0．05)；同时两组患儿血清IL一6、TNF一仅和IFN一-y水平均明显下降(P<0．05或P

3、3—9701(2014)02—0036—03EffectofbifidobacteriamtetravaccinetabletsinthetrectmentofchildrenwithrotaviralenteritisanditsinfluenceonserumcytokineHELiuHUWenhui1．DepartmentofPaediatrics，PujiangTraditionalChineseMedicineHospitalinZhejiangProvince，Pujiang，322200China；2．

4、DepartmentofPaediatrics，TaizhouHospital，TaizhouEnzeMedicalCenter(Group)inZhejiangProvince，Linhai，317000China[Abstract]ObjectiveTodiscusscurativeefectofbifidobacteriumtetravaccineTabletsonchildrenwithRotaviralEnteritisanditsinfluenceonserumcytokine．MethodsAtotal

5、of68casesofchildrenwithRotaviralEnteritisweredividedintoobservationgroupandcontrolgroup．Thechildrenincontrolgroupwereonlygiventhemedicaltreatmentsuchlikedietadjustment，anti—virus，fluidinfusion，correctionofelectrolytedisturbances，acid—baseimbalanceandetc．Thepati

6、entsinobservationgroupwereadditionallygivenbifidobacteriumtetravaccinetabletsonthebasisofthemedicaltreatmentincontrolgroup．ResultsThefever，vomitingandantidiarhealtimesofchildreninobservationgroupweremuchshorterthanthoseincontrolgroup<0．05)．After3days’medicaltre

7、atment，clinicalcurativeeffectofchildreninobservationgroupwasmuchbetterthanthatincontrolgroup(x=4．66，P

8、igherthanthatincontrolgroupbeforeandaftermedicaltreatmentfP<0．05)．ConclusionBifidobacteriumtetravaccinetabletshasreliablecurativeeffectonchildrenwithRotaviralEnteritis，whose