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时间:2020-04-25
《健康体检成人FibroScan检测肝脏硬度值与受控衰减参数的相关分析-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·484·实用肝脏病杂志2o14年9月第l7卷第5期JPracHepatol,Sep.2014.Vo1.17No.5·脂肪性肝病·健康体检成人FibroScan检测肝脏硬度值与受控衰减参数的相关分析卢加发,刘文斌,潘勤,陈光榆,沈峰,章瑞南,朱婵艳,陈一铭,张舒宜,吴佳瑜,范建高【摘要】目的探讨普通人群肝脏硬度测量值(LSM)与受控衰减参数(CAP)之间的关联,为临床研究提供参考。方法在207例成功进行FibroScan检查的健康体检者,获取性别、年龄、体质量指数(BMI)和腰高比(wHtR)资料,分析其LSM和CAP的相关性。结
2、果不同年龄人群LSM的差异无统计学意义,但在BMII>24kgCn~的受试者,其LSM和CAP值分别为(4.60±1.15)kPa和(245.24±55.37)dB/m,均显著高于BMI<24k的受试者[(4.25±1.23)kPa和(215.82±55.47)dB/m,P<0.0o1];WHtR≥0.50的受试者LSM和CAP分别为(4.52±1.22)kPa和(247.04±57.78)dB/m,亦均高于WHtR<0.50的受试者[(4.19±1.15)kPa和(204.65±52.25)dB/m,P<0.05];男性受试者L
3、SM和CAP值亦均高于女性受试者[(4.534-1.23)kPa和(4.11±1.O8)dB/m对(4.114-1.08)kPa和(220.08±57.88)dB/m,P50岁的受试者CAP值[(246.56±59.06)dB/m]高于年龄<50岁的受试者[(222.88±56.60)dB/m];LSM与CAP值呈显著性正相关(r=0.26,P=-O.0002);进一步对各组人群分析发现,在BMI~>24k、WHtR>O.50、男性受试者和年龄≥50岁的受试者中,LSM与CAP值呈显著性正相关(P4、,其中在BMI≥24kg/n~组人群,两者呈非常显著性正相关(r=0.37,P<0.01);通过相关分析发现,LSM和CAP均与BMI、WHtR和性别相关(尸5、肝脏硬度测量值;受控衰减参数;瞬时弹性成像技术;体检DOh10.39696.issn.1672-5069.2014.05.010AcorrelationofHverstifnesstocontroHedattenuationparameterinhealthyindividualsLu五,LiuWenbin,PanQin,eta1.DepartmentofGastroenterology,XinhuaHospital,ShanghaiJiaoTongUniversitySchoolofMedicine,Shanghai2000926、,China【Abstract】ObjectiveToexplorethecorrelationbetweenliverstifnessmeasurement(LSM)andcontrolledattenuationparameter(CAP)inthegeneralpopulation.MethodsAcorrelationofLSMtoCAPwasconductedinatotalof207participantswhoweresuccessfullyexaminedbyFibroScaninageneralhealthexa7、mination,and.thedataincludinggender,age,bodymassindex(BMI)andwaistheightradio(WHtR)wererecorded.ResultsTheLsMandCAPinoverweightandobeseparticipants(BMI≥24kg/m)werehigherthanthoseinleanparticipants(BMI<24ks/m)[(4.60~1.15)kPavs.(4.25~1.23)kPa,P<0.001and(245.24~55.37)dB/8、mvs.(215.82+55.47)dB/m.P
4、,其中在BMI≥24kg/n~组人群,两者呈非常显著性正相关(r=0.37,P<0.01);通过相关分析发现,LSM和CAP均与BMI、WHtR和性别相关(尸5、肝脏硬度测量值;受控衰减参数;瞬时弹性成像技术;体检DOh10.39696.issn.1672-5069.2014.05.010AcorrelationofHverstifnesstocontroHedattenuationparameterinhealthyindividualsLu五,LiuWenbin,PanQin,eta1.DepartmentofGastroenterology,XinhuaHospital,ShanghaiJiaoTongUniversitySchoolofMedicine,Shanghai2000926、,China【Abstract】ObjectiveToexplorethecorrelationbetweenliverstifnessmeasurement(LSM)andcontrolledattenuationparameter(CAP)inthegeneralpopulation.MethodsAcorrelationofLSMtoCAPwasconductedinatotalof207participantswhoweresuccessfullyexaminedbyFibroScaninageneralhealthexa7、mination,and.thedataincludinggender,age,bodymassindex(BMI)andwaistheightradio(WHtR)wererecorded.ResultsTheLsMandCAPinoverweightandobeseparticipants(BMI≥24kg/m)werehigherthanthoseinleanparticipants(BMI<24ks/m)[(4.60~1.15)kPavs.(4.25~1.23)kPa,P<0.001and(245.24~55.37)dB/8、mvs.(215.82+55.47)dB/m.P
5、肝脏硬度测量值;受控衰减参数;瞬时弹性成像技术;体检DOh10.39696.issn.1672-5069.2014.05.010AcorrelationofHverstifnesstocontroHedattenuationparameterinhealthyindividualsLu五,LiuWenbin,PanQin,eta1.DepartmentofGastroenterology,XinhuaHospital,ShanghaiJiaoTongUniversitySchoolofMedicine,Shanghai200092
6、,China【Abstract】ObjectiveToexplorethecorrelationbetweenliverstifnessmeasurement(LSM)andcontrolledattenuationparameter(CAP)inthegeneralpopulation.MethodsAcorrelationofLSMtoCAPwasconductedinatotalof207participantswhoweresuccessfullyexaminedbyFibroScaninageneralhealthexa
7、mination,and.thedataincludinggender,age,bodymassindex(BMI)andwaistheightradio(WHtR)wererecorded.ResultsTheLsMandCAPinoverweightandobeseparticipants(BMI≥24kg/m)werehigherthanthoseinleanparticipants(BMI<24ks/m)[(4.60~1.15)kPavs.(4.25~1.23)kPa,P<0.001and(245.24~55.37)dB/
8、mvs.(215.82+55.47)dB/m.P
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