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时间:2020-04-23
《不同水解程度乳清蛋白配方奶辅助治疗婴儿湿疹疗效观察-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、141中华临床营养杂志2014年6月第22卷第3期ChineseJournalofClinicalNutrition,June2014,Vo1.22,No.3·论著·不同水解程度乳清蛋白配方奶辅助治疗婴儿湿疹疗效观察吴红媛张筱佼林伟婉【摘要】目的探讨深度水解乳清蛋白配方奶及适度水解乳清蛋白配方奶作为婴儿湿疹辅助治疗措施的临床价值。方法将59例人工喂养患有婴儿湿疹的足月儿按喂养配方不同分为深度水解乳清蛋白配方组(eHF组,n=18)、适度水解乳清蛋白配方组(pHF组,n=22)及普通牛奶配方组(CMF组,n=19),在外用药物治
2、疗相同的情况下,利用特应性皮炎积分指数观察治疗的有效率、缓解率等。结果治疗2周后eHF组治疗有效率38.9%及缓解率50.0%,与CMF组的5.3%及31.6%相比差异有统计学意义(=12.225,P=0.002);pHF组治疗有效率9.1%及缓解率40.9%,与CMF组相比差异无统计学意义(X2=0.761,P:0.683)。治疗8周后,eHF组治疗有效率55.6%及缓解率38.9%,与CMF组的15.8%及47.4%相比差异有统计学意义(=8.498,P=0.014);pHF组治疗有效率31.8%及缓解率59.1%有高于C
3、MF组的趋势,但差异无统计学意义(=4.912,P=0.086)。治疗前(F=0.773,P=0.466)、后(F=1.313,P=0.277)d,JL生长发育指标各组间差异无统计学意义。结论深度水解乳清蛋白配方及适度水解乳清蛋白配方奶均可辅助治疗婴儿湿疹,但深度水解配方治疗显效较快。【关键词】水解乳清蛋白;婴儿配方;食物过敏;婴儿湿疹【中图分类号】R758.23;R723【文献标志码】A【文章编号】1674-635X(2014)03.0141.04Roleofwheyproteinhydrolyzedformulaasana
4、djunctivetherapyfortreatingpatientswithinfantileec-zemaWuHongyuan,Zhang~(iaofiao,LinWeiwan.ChildHealthDivision,ZhuhaiMaternityandChildHealthHospital,Zhuhai,Guangdong519000,ChinaCorrespondingauthor:WuHongyuan,E—mail:whypql3@126.con【Abstract】ObjectiveTostudytheclinica
5、lvalueofextensivelywheyproteinhydrolyzedformulaandpartiallywheyproteinhydrolyzedformulaasanadjunctivetherapyintreatinginfantileeczema.MethodsTo-tally59bottle—feedingbabieswit},infantileeczemaweredividedintothreegroupsdependingondifferentformulafeeding:extensivelyhyd
6、rolyzedformulafeedinggroup(eHFgroup,n=18),partiallyhydrolyzedformulafeed-inggroup(pHFgroup,n=22),andconventionalCOW’Smilkformulafeedinggroup(CMFgroup,n=19).Meanwhile,allpatientsreceivedthesamedrugtreatment.TheeffectiverateandremissionratewereevaluatedusingtheSCORing
7、AtopicDermatitis(SCORAD)index.ResultsAfter2weeksoftreatment,theeffectiveratewas38.9%andtheremissi·3nratewas50.0%intheeHFgroup.whichweresignificantlydifferentfromthoseintheCMFgroup(5.3%and31.6%)(X2=12.225,P=0.002).Theeffectiveratewas9.1%andtheremissionratewas40.9%int
8、hepHFgroup.showingnosignificantdifferencewhencomparedwiththeCMFgroup(=0.761,P=0.683).After8weeksoftreatment,theeffectiveratewas55.6%andthe
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