肝癌术后早期复发临床危险因素的分析.pdf

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1、中华肿瘤防治杂志2009年2月第16卷第3期CHINJCANCERPREVTREAT,February2009,Vol.16No.3#219#×临床应用研究Ø肝癌术后早期复发临床危险因素的分析苗雄鹰,文宇,胡继雄,戴卫东中南大学湘雅二医院普外科,湖南长沙410011FactorsforearlypostoperativerecurrenceofhepatocelluarcarcinomaMIAOXiong-ying,WENYu,HUJi-xiong,DAIWei-dongDepartmentofGeneralSurgery,SecondXiangyaHospitalofCentralSouth

2、University,Changsha410011,P.R.China=摘要>目的:探讨肝癌术后早期复[ABSTRACT]OBJECTIVE:Toinvestigatetheriskfactorsforearly发的各项危险因素。方法:回顾性分postoperativerecurrenceofhepatocelluarcarcinoma.METHODS:Atotal析111例肝癌切除术后患者的资料,of111casesofhepatocellularcarcinomaunderwentresectionwereretro-探讨各项临床病理因素与肝癌术后spectivelyreviewedwit

3、hregardtotheclinicaldata,pathologicalcharac-早期复发([1年)的关系。结果:111teristics,andsurvivalrate.RESULTS:Forty-onecases(3619%)exper-i例肝癌根治性切除病例中,早期复发encedearlyrecurrence([1year).Univariateanalysisdemonstratedthat41例(3619%)。单因素分析表明,肿thesizeoftumor,satellitelesion,portalveintumoremboliandpostoper-癌大小、有无子灶、脉管癌

4、栓及术后ativeregionalchemotherapywereindependentriskfactorsforearlyrecur-区域化疗对术后早期复发有影响。rence.Multivariateanalysisdemonstratedthatsatellitelesion,portalvein多因素分析表明,有无子灶、脉管癌tumoremboliandpostoperativeregionalchemotherapywereindependent栓和术后区域化疗是影响术后早期riskfactorsforearlyrecurrence.Thesurgicaltreatmentforth

5、eearlyre-复发的独立因素。早期复发组经外currenceachieved1-and2-yearsurvivalratesof6519%and1416%re-科治疗后1、2年生存率为6519%和spectively,whichweresignificantlyhigherthanthoseofthecasesre-1416%,明显高于姑息性治疗者,P

6、motherapyareindependent术后区域化疗是影响肝癌术后早期riskfactorsfortheearlypostoperativerecurrenceofhepatocellularcarc-i复发的重要因素,早期复发积极外科noma.Theprompttreatmentwithsurgicalapproachfortherecurrence处理能有效提高生存率。caneffectivelyimprovethesurvival.中华肿瘤防治杂志,2009,16(3):219-221ChinJCancerPrevTreat,2009,16(3):219-221=关键词>肝肿瘤;复

7、发;危险因素[KEYWORDS]liverneoplasms;recurrence;riskfactors=中图分类号>R735.7=文献标识码>A=文章编号>1673-5269(2009)03-0219-03对肝细胞癌(hepatocellularcarcinoma,HCC)来2001-01-2004-12我院收治423例HCC患者,行说,手术切除是目前主要的治疗方法。近年来,肝癌生手术切除12