CT检测正常成人不同脑区代谢水平性别和年龄的差异-论文.pdf

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1、中国医学影像技术2014年第3O卷第9期ChinJMedImagingTechnol，2014，Vot30，No9·1339·◆：◆中枢神经影像学Ageandgenderrelatedmetabolismdifferencesindifferentcerebralregionsinhealthyadultsusing坞F—FDGPET／CTSHAOXiao-liang，SHAOXiao—nan，WANGXiao—song，XUMei，WANGYue-tao(DepartmentofNuclearMedicine，t

2、heThirdA{{tliatedHospitalofSoochowUniversity，Changzhou213003，China)~Abstract]0bjectiveToexploretheageandgenderrelatedmetabolismdifferencesindifferentcerebralinhealthyadultsusing”F-FDGPET／CT．MethodsBrain。F-FDGPET／CTdataof769healthyadultswereretr0spective1yanaly

3、zed．Thesubjectsweredividedinto≤30yearsold，31—4Oyearsold，41—5Oyearsold，51—6Oyearsold，61—7Oyearsoldand≥71yearsoldgroup．ThePETimagesofthebrainwasstandarizatedandthedifferentregionsofrightandleftincludingfrontallobe，temporallobe，parietallobe，cingulategyrus，central

4、area，occipitallobe，calcarineandsurroundingcortexcerebel—lum，basalganglia，medialtemporallobeandcerebellarwereautomaticallyoutlinedbySceniumsoftware．Themeanstand—ardizeduptakevalue(SUVme日)ofeachregionwereassessedandcomparedbetweenmalesandfemales，aswellasdifferen

5、tagegroups．ResultsNodifferencesofSUV一inbilateralcentralarea，calcarineandsurroundingcortexcerebellum(bothP>O．05)andsignificantdifferencesofSUV一intheotherregions(allP

6、tallobe，parietallobe，cingulategyrus，centralarea，calcarineandsurroundingcortexcerebellumandcerebellum，dominantregionsontherightincludedtemporallobe，occipitallobeandmedialtemporallobe．Therightbasalgangliawasdominantinmaleswhiletherewasnodifferentbetweenrightandl

7、eftinfemales．SUVm柏inallregionsexceptforcerebellumdecreasedalongwithage，whichwasmoreobviousontheleft．ConclusionThereareageandgenderrelatedmetabolismdifferencesindifferentcerebralinhealthyadults，andthemetabolismshowsasymmetricalreductioninrightandlefthemishereal

8、ongwithage．[Keywords]Brain；Tomography，emission-computed；Metabolism；Sexfactors；AgefactorsF-FDGPET／CT检测正常成人不同脑区代谢水平性别和年龄的差异邵晓梁，邵小南，王小松，徐梅，王跃涛(苏州大学附属第三医院核医学科，江苏苏州213003)[摘要]目的采用”F-FDG