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时间:2020-04-21
《CT引导下经皮髂骨成形术治疗髂骨转移性肿瘤-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、华西医学2013,28(5)WestChinaMedicalJournal,Vo1.28,No.5May2013719论著CT引导下经皮髂骨成形术治疗髂骨转移性肿瘤游昕,腾昊歧,廖正银,蒲吉【摘要】目的探讨CT引导下髂骨成形术在治疗恶性肿瘤晚期髂骨转移中的价值。方法对2009年3月一2011年8月收治的12例经病理活检证实为恶性肿瘤髂骨转移患者共,分别行CT引导下骨水泥注入髂骨成形术并观察该组患者治疗后的疼痛缓解、生活质量改善及生存期等。结果该组患者手术后24h内,疼痛与术前相比差异无统计学意义(t=2.433,P>0.05),手术后3d和7
2、d进行再次评估,与治疗前相比差异有统计学意义(t=3,123,3.124;P<0.05);术后该组患者在躯体功能、心理功能、社会功能、物质生活状态方面的生活质量评分显著高于手术前(t=-2.341,2.354,3.567,3.124;P<0.05)。该组总有效率为82.5%。且治疗后癌胚抗原(CEA)含量为(2.9士0.9)/L,显著低于治疗前的(15.54-3.2)g,L(户3、%,均为出现了无症状的骨水泥渗漏现象,注射治疗后持续时间为0.5~3h,平均1.87h。结论髂骨成形术短期内可明显减轻恶性肿瘤髂骨转移所致的疼痛症状。CT引导下髂骨成形术安全、可靠、近期疗效确切,是姑息性治疗恶性肿瘤髂骨转移的有效方法之一。【关键词】骨水泥;髂骨;恶性肿瘤;骨成形术;转移瘤【文献标识码】ADOI:10.7507/1002—0179.20130224CTGuidedPercutaneousOsteoplastyofIliumtoTreatMetastaticTumorofIliumYOUXin.TENGHao—qi,LIAOZh4、eng-yin.PUJiDepartmentofOncology,WestChinaHospital,ChengduSichuan610041PR.ChinaCorrespondingauthor:LIAOZheng-yin,E—mail:zhengyinliao@sina.vip.com[Abstract]ObjectiveTodiscussthevalueofCTguidedpercutaneousosteoplastywithbonecementinthetreatmentofmetastatictumorofilium.Methods5、Thisresearchcollectedtheclinicaldataof12patientswithmetastatictumorofiliumundergoingosteoplastyundertheguidanceofCTscanningbetweenMarch2009andAuguest2011.Weobservedpainalleviation,lifequalityimprovementandsurvivalconditionofallthepatientsduringthetwo-yearfollow—up.ResultsVA6、Sscoresofthepatientsdidnotchangesignificantlyaftertreatment(t=-2.433,P>0.05),andduringthereassessmentthreeandsevendaysafterthetreatment,VASscoresweresignificantlydifferent(t=3.123and3.124,P<0.05).Aftersurgery,patients’physicalfunction,psychologicalfunction,socialfunctionand7、materiallifeconditionintermsofqualityofli~scoresignificantlyincreased(t=-2.341,2.354,3.567,and3.124,P<0.05).Thetotaleffectiveratewas82.5%.CEAlevelsaftertreatmentwas(2.94-0.9)/L,whichwassignificantlylowerthanthatbeforetreatment(15.5土3.2)/L,P<0.O1).Allpatientswerefollowedupfo8、roneyear,andthehalf-year,ten—monthand12一monthsurvivalrateswererespectively15.2%,32
3、%,均为出现了无症状的骨水泥渗漏现象,注射治疗后持续时间为0.5~3h,平均1.87h。结论髂骨成形术短期内可明显减轻恶性肿瘤髂骨转移所致的疼痛症状。CT引导下髂骨成形术安全、可靠、近期疗效确切,是姑息性治疗恶性肿瘤髂骨转移的有效方法之一。【关键词】骨水泥;髂骨;恶性肿瘤;骨成形术;转移瘤【文献标识码】ADOI:10.7507/1002—0179.20130224CTGuidedPercutaneousOsteoplastyofIliumtoTreatMetastaticTumorofIliumYOUXin.TENGHao—qi,LIAOZh
4、eng-yin.PUJiDepartmentofOncology,WestChinaHospital,ChengduSichuan610041PR.ChinaCorrespondingauthor:LIAOZheng-yin,E—mail:zhengyinliao@sina.vip.com[Abstract]ObjectiveTodiscussthevalueofCTguidedpercutaneousosteoplastywithbonecementinthetreatmentofmetastatictumorofilium.Methods
5、Thisresearchcollectedtheclinicaldataof12patientswithmetastatictumorofiliumundergoingosteoplastyundertheguidanceofCTscanningbetweenMarch2009andAuguest2011.Weobservedpainalleviation,lifequalityimprovementandsurvivalconditionofallthepatientsduringthetwo-yearfollow—up.ResultsVA
6、Sscoresofthepatientsdidnotchangesignificantlyaftertreatment(t=-2.433,P>0.05),andduringthereassessmentthreeandsevendaysafterthetreatment,VASscoresweresignificantlydifferent(t=3.123and3.124,P<0.05).Aftersurgery,patients’physicalfunction,psychologicalfunction,socialfunctionand
7、materiallifeconditionintermsofqualityofli~scoresignificantlyincreased(t=-2.341,2.354,3.567,and3.124,P<0.05).Thetotaleffectiveratewas82.5%.CEAlevelsaftertreatmentwas(2.94-0.9)/L,whichwassignificantlylowerthanthatbeforetreatment(15.5土3.2)/L,P<0.O1).Allpatientswerefollowedupfo
8、roneyear,andthehalf-year,ten—monthand12一monthsurvivalrateswererespectively15.2%,32
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