云南省鹤庆县氯硝柳胺泥敷灭螺效果观察.pdf

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1、·12·生旦筮!鲞筮翅rasitosesandInfectiousDiseasesMar．2012．v01．10．No．1【论著】云南省鹤庆县氯硝柳胺泥敷灭螺效果观察李炳桂，李文豹，董毅，冯锡光，母亮先，田淑惠，李萍，董兴齐[摘要]目的观察氯硝柳胺泥敷灭螺在云南大山区的试验效果。方法在鹤庆县血吸虫病流行区，采用氯硝柳胺不同药物剂量进行现场泥敷灭螺，灭螺后180d内连续观察6次钉螺变化情况和泥敷药泥对钉螺的持续灭螺效果。结果鹤庆县泥敷灭螺试区各药物组钉螺死亡率为51．28％一100．00％，各药物组60d钉螺死亡率达到76

2、．74％以上，90d钉螺死亡率达到92．11％以上。药泥室内浸出液和现场沟渠浸出液杀螺试验显示，随着药物浓度的增加钉螺死亡率增高；随着时间的延长钉螺的死亡率降低。灭螺15、30d后8g／in组及12g／m组仍有较强的杀螺效果，90d各组仍有一定的杀螺作用。结论氯硝柳胺泥敷灭螺效果较好，在云南高原平坝地区和高原峡谷地区具有一定的推广使用价值。[关键词]钉螺；氯硝柳胺；泥敷[中图分类号]R383．24[文献标识码]A[文章编号]1672～2116(2012)01—012一O6EffectofSoilPastingMixedW

3、ithNiclosamidetoControlYunnanSnailinHeqingCountyLIBing—gui，LIWen—bao，DONGYi，FENGXi-guang，MULiang．xian，TIANShu—hui，LIPing，DONGXing-qi．1HeqingStationofSchistosomiasisControl，Heqing675100，YunnanProvince，China．2YunnanProvincialInstituteofEndemicDiseaseControlandPreve

4、ntion，Dali671000，YunnanProvince，China．AbstractObjectiveToevaluatetheefectofsnailcontrolthroughsoilpastingmixedwithNiclosamideinYun—nanmountainousareas．MethodsSchistosomiasisepidemicareasinHeqingcountywereselected，andsoilpastingmixedwithdifferentdosageNiclosamidew

5、asconducted．Thechangeofsnailandtheeffectofsnai1controlbysoilpastingwereobserved6timescontiniouslyin180daysaftersnailcontro1．ResultsThemot—talityrateofsnailwasfrom51．28％to100．0％withdifferentdosagegroupswhichthroughsoilpastingmixedwithniclosamide．Themortalityrateof

6、snailwasmorethan76．74％inallgroupsafter60days，andmorethan92．11％after90days．ThekillingsnailtestbyusingindoorlixiviatedliquidofsoilwithNiclosamideandthelixiviatedliquidofditchshowedthatthesnailmortalityrateswereincreasedalongwiththehigherdruglev—e1．Themortalityrates

7、ofsnailweredecreasedalongwiththeextensionoftime．After15daysand30daysofkillingsnail，the8g／mgroupandthe12g／mgroupstillhadstrongeffectofkillingsnail，eachgroupstillhadcertaineffectafter90days．ConclusionsSoilpastingmixedwithNiclosamidetokillsnailhasgoodefectandworthge

8、neralizingintheplateauflatnessregionandtheplateaucanyonregioninYunnan．Keywordssnail；Niclosamide；soilpasting作者单位：l云南省鹤庆县血吸虫病防治站(云南鹤庆泥敷灭螺作为一种新的灭螺方法在四川省血吸671500)虫