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时间:2020-04-20
《顺苯磺酸阿曲库铵对兔定量药物脑电图α1、α2频段的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、《中国医学创新》第ll卷第18期(总第300J~)2014年6月基础研究Jichuyanjiu顺苯磺酸阿曲库铵对兔定量药物脑电图OLl、OL2频段的影响水赵丽艳①蔡慧明②韩平平②王虹②戴体俊②【摘要】目的:观察顺苯磺酸阿啦库铵对兔定量药物脑电图(QPEEG)IX、IX频段的影响。方法:采用QPEEG功率谱分析法,分析兔耳缘静脉注射顺苯磺酸阿曲库铵0.3mg/kg前后IX。、IX频段功率百分比的变化。结果:与给药前比较,各脑区IX频段功率百分比在给药后各时间点(除右额在5min、40min稍降低)均增加,且左额、右顶、右枕及颞区在个别时
2、间点的比较差异均有统计学意义(P<0.05或P<0.01o与给药前比较,各脑区IX:频段功率百分比在给药后各时间点(除左顶在5min,左枕在l0min稍降低)均增加,且额、顶及左颢区在各时间点的比较差异均有统计学意义(P3、HAOLi—yan,CAIHui-ming,HANPing-ping,etaid/MedicalInnovationofChina,2014,11(18):049—051【Abstract】Objective:Toinvestigatetheeffectsofcisatracuriumbesylateon1一bandand2一bandofquantitativepharmaco—electr0encphalography(QPEEG)inrabbits.Method:Thechangesofpowerpercentageofd1一ba4、ndando【2一bandofQPEEGwereanalyzedbypowerspectralanalysistechniqueinrabbitsbeforeandafterintravenouslyinjectedwith0.3mg/kgcisatracuriumbesylate.Result:Comparedwiththebaseline,thepowerpercentageof1一bandofeachbrainregionwasincreasedateachtimepointexcept5minand40minintherigh5、tfrontalafterdruginfusions,andtheleftfrontal,rightparietal,rightoccipitalandtemporalareasintheindividualtimepoints,thedifferenceshadstatisticalsignificance(P<0.05orP<0.01).Incontrasttothebaseline,thepowerpercentageof2-bandofeachbrainregionwerealsoincreasedateachtimepoin6、texcept5minintheleftparietaland10minintheleftoccipitalafterdruginfusions,thefrontal,parietalandlefttemporalareasintheindividualtimepoints,thedifferenceshadstatisticalsignificance(P7、-bandofQPEEGinrabbits.【Keywords】Cisatracuriumbesylate;Quantitativepharmaco—EEG;Powerspectral—analysisFirst-author’Saddress:LuoyangOrthopedic-traumatologicalHospital,Luoyang471002,Chinadoi:10.3969~.issn.1674—4985.2014.18.016定量药物脑电图(quantitativepharmaco—少各参数的变异系数。本研究采用目前临8、床上常用的electroencephalography,QPEEG)是药物引起脑功能变肌松药一顺苯磺酸阿曲库铵(cisatracuriumbesylate),化的客观指标,已在神经病学、精神病学等方面得到来观察它对兔QP
3、HAOLi—yan,CAIHui-ming,HANPing-ping,etaid/MedicalInnovationofChina,2014,11(18):049—051【Abstract】Objective:Toinvestigatetheeffectsofcisatracuriumbesylateon1一bandand2一bandofquantitativepharmaco—electr0encphalography(QPEEG)inrabbits.Method:Thechangesofpowerpercentageofd1一ba
4、ndando【2一bandofQPEEGwereanalyzedbypowerspectralanalysistechniqueinrabbitsbeforeandafterintravenouslyinjectedwith0.3mg/kgcisatracuriumbesylate.Result:Comparedwiththebaseline,thepowerpercentageof1一bandofeachbrainregionwasincreasedateachtimepointexcept5minand40minintherigh
5、tfrontalafterdruginfusions,andtheleftfrontal,rightparietal,rightoccipitalandtemporalareasintheindividualtimepoints,thedifferenceshadstatisticalsignificance(P<0.05orP<0.01).Incontrasttothebaseline,thepowerpercentageof2-bandofeachbrainregionwerealsoincreasedateachtimepoin
6、texcept5minintheleftparietaland10minintheleftoccipitalafterdruginfusions,thefrontal,parietalandlefttemporalareasintheindividualtimepoints,thedifferenceshadstatisticalsignificance(P7、-bandofQPEEGinrabbits.【Keywords】Cisatracuriumbesylate;Quantitativepharmaco—EEG;Powerspectral—analysisFirst-author’Saddress:LuoyangOrthopedic-traumatologicalHospital,Luoyang471002,Chinadoi:10.3969~.issn.1674—4985.2014.18.016定量药物脑电图(quantitativepharmaco—少各参数的变异系数。本研究采用目前临8、床上常用的electroencephalography,QPEEG)是药物引起脑功能变肌松药一顺苯磺酸阿曲库铵(cisatracuriumbesylate),化的客观指标,已在神经病学、精神病学等方面得到来观察它对兔QP
7、-bandofQPEEGinrabbits.【Keywords】Cisatracuriumbesylate;Quantitativepharmaco—EEG;Powerspectral—analysisFirst-author’Saddress:LuoyangOrthopedic-traumatologicalHospital,Luoyang471002,Chinadoi:10.3969~.issn.1674—4985.2014.18.016定量药物脑电图(quantitativepharmaco—少各参数的变异系数。本研究采用目前临
8、床上常用的electroencephalography,QPEEG)是药物引起脑功能变肌松药一顺苯磺酸阿曲库铵(cisatracuriumbesylate),化的客观指标,已在神经病学、精神病学等方面得到来观察它对兔QP
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