[精品][经典]调脂汤治疗非酒精性脂肪肝临床疗效观察.doc

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1、[经典]调脂汤治疗非酒精性脂肪肝临床疗效观察调脂汤治疗非酒精性脂肪肝临床疗效观察【摘耍】目的：探讨调脂汤治疗非酒精性脂肪肝的临床疗效。方法：按诊断标准选择非酒精性脂肪肝患者162例，随机分为两组，治疗组、对照组各81例。治疗组服用调脂汤；对照组服用东宝肝泰片，治疗前后详细记录两组患者评定指标,实验完成后对数据进行整理分析。结果：治疗组总体疗效优于对照组，两组比较卩V0.05,差异有显著性意义。其中，在降血脂方面，两组治疗前后组内比较具有明显差异，PV0.05；但治疗后两组间比较无明显差异，P>0.05；在改善肝功能方面，两者血清ALT、AST下降存在明显差异，P<0.05o结论：调

2、脂汤治疗非酒精性脂肪肝疗效明显优于东宝肝泰片，其机理可能是通过改善肝细胞功能及降血脂实现的。【关键词】非酒精性脂肪肝；调脂汤TheobservingofclinicaleffectofTiaoZhiSouptreatingwithnon-alcoholicfatty1iverdisease・Auther:MiaoXiangdong;Correspond!ng:FuHuaicheng(HezeChinesemedicinehospitalShandongProvinceHeze274000)[Abstract]Goal:ToexploretheclinicaleffectofTiao

3、ZhiSoupontreatingthenon-alcoholicfattyliverdisease・Method:Accordingtothediagnosisstandard,choosingthenon-alcoholicfatty1iverpatient162examplesaltogether・Thepatientswererandomlydividedintotwogroups:Thetreatmentgroupandthecontrolgroup.Eachgrouphave81examples.ThetreatmentgroupwastreatedwithTiaoZh

4、iSoupandthecontrolgroupwastreatedwithDongbaoLiverPiece・Aroundthetreatment,therelatedindicatorsoftwogroupswererecordedindetail,inordtoreorganizatandanalysisthedataaftertheexperimentFinally:Theoverallcurativeeffectoftreatmentgroupissuperiortothecontrolgroup,卩〈0.05,bothwasthesignificantdifference

5、・0ntheaspectofreducingbloodlipids,twogroupsweretheobviousdifferencebeforetreatment,P〈0・05;Butafterthetreatment,thechangesoftwogroup'sbloodlipidswerenotobviousdifferent・,P〉0・05;Ontheaspectofimprovementliverfunction,bothbloodserumALT,ASTwereobviousdifference,P〈0.05.Conclusion:TiaoZhiSoupcurative

6、effectissuperiortotheDongbaoLiverPieceobviouslyontreatthenon-alcoholicfattyliver・Itsmechanismistoreducethebloodlipidsandimprovelivercellfunctionpossibility・［Keyword】Thenon-alcoholicfattyliverdisease;TiaoZhiSoup非酒精性脂肪性肝病(NAFLD)是指除外酒精和其他明确的损肝因素所致的，以弥漫性肝细胞大泡性脂肪变为主要特征的临床病理综合征，包括单纯性脂肪肝以及由其演变的脂肪性肝炎(

7、NASH)和肝硬化。随着肥胖和糖尿病的发病率增加，NAFLD现已成为我国常见的慢性肝病之一，严重危害人体健康［1］。笔者根据非酒精性脂肪肝的中医病因病机特点，以调脂汤为主治疗该病，取得较好疗效，现报告如下：1临床资料1.1一般资料162例非酒精性脂肪肝患者均为我院门诊就诊患者,随机分为两组，治疗组81例,男57例，女24例;年龄21~68岁，平均(44・2±7・6)岁；病程0.5-15年。B超分级：轻度19人，中度19人，重度3人。对照组81例，男51例，女30例；年