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时间:2020-04-19
《高通量透析对维持性血液透析患者钙磷代谢的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、昆明医科大学学报2014,35(9):141~143CN53—1221/RJournalofKunmingMedicalUniversity高通量透析对维持性血液透析患者钙磷代谢的影响蔡艳,白云霞,张永新,杨才,李万碧,郭燕(个旧市人民医院肾内科,云南个旧661000)[摘要]目的探讨高通量透析(high—fluxhemodialysis,HFHD)对维挣胜血液透析(maintenancehemodia—lysis,MHD)患者钙磷代谢的影响.方法选择自2012年8月至2014年2月在个旧市人民医院住院的MHD患者86例,随机将患者分为观察组和对照组,观察组43例采取HFHD治疗;而对照组
2、43例则给予低通量透析(1ow—fluxhemodialysis,LFHD)治疗.2组患者均透析6个月.治疗前后测量2组患者的血钙、血磷、甲状旁腺激素(iPTH)和钙磷乘积等指标.结果2组患者治疗前血钙、血磷、iPTH和钙磷乘积相比,差异无统计学意义(P>0.05);治疗后,观察组血钙、血磷、iPTH和钙磷乘积分别为(3.2±0.3)mmo1]L、(1.8±0.2)mmo1]L、(156.5±32.8)pg/mL和(32.54-3.6)mf/dL2,对照组为(2.14-0.4)mmol/L、(2.14-0.2)mmol/L、(387.24-74.5)pg/mL和(47.14-4.3)mg2
3、/dL:,2组上述指标相比,差异具有统计学意义(P<0.05).结论HFHD在MHD患者的透析治疗中,能明显清除血磷和iPTH,提高血钙水平,进而改善患者钙磷代谢状态.[关键词]高通量透析;维持性血液透析;钙磷代谢[中图分类号]R692[文献标识码]A[文章编号]2095-610X(2014)09-0141-03ClinicalStudyontheEffectsofHigh-fluxHemodialysisonCalciumandPhosphorusMetabolisminPatientswithMaintenanceHemodialysisCAIYan,BAIYun—xia,ZHANGY
4、ong-xin,YANGCai,LIWan—bi,GUOYan(Dept.ofNephrology,ThePeople’HospitalofGejiuCity,CejiuYunnan661000,China)[Abstract]ObjectiveToobserveandexploretheeffectsofhigh-fluxhemodialysis(HFHD)oncalciumandphosphorusmetabolisminpatientswithmaintenancehemodialysis(MHD).MethodsEighty-sixpatientswithMHDinourhospi
5、talfromAugust2012toFebruary2014wereselectedandrandomlydividedintotheobservationgroupandthecontrolgroup.43casesintheobservationgroupweretreatedwithHFHD,while43patientsinthecontrolgroupweretreatedwithlow-fluxhemodialysis(LFHD).Allpatientsacceptedhemodialysisfor6months.Calcium,phosphorus,parathyroidh
6、ormone(iPTH)andcalcium-phosphorusproductweremeasuredandcomparedinthetwogroupsbeforeandafterhemodialysis.ResultsThedifferencesofcalcium,phosphorus,iPTHandcalcium-phosphorusproductbetweentwogroupsbeforetreatmentwerenotstatisticallysignificant(P>0.05).Afterhemodialysis,calcium,phosphorus,iPTHandcalci
7、um-phosphorusproductwere(3.2±0.3)mmol/L,(1.8±0.2)mmol/L,(156.5±32.8)pg/mLand(32.5±3.6)mgZ/dL2intheobservationgroup,andwere(2.14-0.4)mmol/L,(2.14-0.2)mmol/L,(387.24-74.5)pg/mLand(47.1±4.3)mg2/dL2inthecontrolgroup,
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