欢迎来到天天文库
浏览记录
ID:5346653
大小:251.41 KB
页数:3页
时间:2017-12-08
《血液成分单采术在血液病中的应用及不良反应的观察》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、国际输血及血液学杂志2010年第33卷第4期·293··论著·血液成分单采术在血液病中的应用及不良反应的观察鹿群先李艳杰赵玉凤刘灿侠李振宇徐开林【摘要】目的初步探讨血液成分单采术在血液病治疗中的应用并观察其不良反应。方法对524例患者应用CS-3OOOplus血细胞分离机进行916次治疗性血液成分单采,根据病人情况选择不同细胞收集程序,分析临床效果和实验室指标的改善情况,并分析其不良反应及处理措施。结果行血细胞单采术后210例高白细胞患者白细胞由(230.1±48.5)X10。/L降至(49.3_-4-10.0)×10。/L;123例真性红细胞患者血红蛋白由(216.0±23
2、.o)g/L降至(150.0±12.0)g/L,红细胞由(7.1±0.5)×10/L降至(4.3±0.8)×1o”/L;158例高血小板患者血小板由(1080.0±314.O)×10。/I降至(341.0±82.O)×10。/L,治疗前后差异均有统计学意义(P3、效肯定且安全可靠、不良反应少,并对提高临床药物治疗效果有很大意义。【关键词】血细胞分离机;血细胞单采术;血浆置换术ApplicationofHemapheresisonTreatmentofHematologyandObservationoftheAdverseReactionLUQun一.;cian,LJYan—jie,ZHAOYufeng,LIUCan—xia,LZhen—yu,XUKai—lin.DepartmentofHematology,PAffiliatedHospitalofXuzhouMedicalCollege,Xuzhou221002,ChinaC0rrP4、声0author:XUKai—lin,Email:lihmd@l63.corn[Abstract]ObjectiveToinvestigatetheclinicaleffectoftherapeutichemapheresisandobservetheadversereaction.MethodsCS-3000plusbloodcellseparatorwasusedfortherapeutichemapheresisin524patients.Weselectedthedifferentcellcollectionproceduresaccordingtothepatien5、tsconditionsandanalyzedtheclinicaleffects,thelaboratoryindexes,theadversereactionsandcorrespondinghandlings.ResultsAftertherapeutichemapheresis,theleucocytecountswasdecreasedfrom(230.1±48.5)×10/Ito(49.3±10.0)×10。/Lin210patientswithhighwhitebloodcell,thehemoglobinwasdecreasedfrom(216.0±23.O)6、g/Ito(150.0±12.0)g/Landtheerythrocytecountswasdecreasedfrom(7.1±0.5)×1O/Lto(4.3±0.8)×1012/Lin123patientswithpolycythemiavera,theplateletcountswasdecreasedfrom(1080.0±314.O)×10/Ito(341.0±82.0)X10。/Lin158patientswithhighplatelet.Thereweresignificantdifferences(P<0.01)beforeandaftertreatment.T7、hesignificantimprovementofclinicalsymptomsandlaboratoryindexesweregainedin90.6patientswithTTPaftertherapeuticplasmaticexchangebyCS3000plusbloodcellseparator.Therewereafewincidencesofcitrussaltpoisoning(3.0),hypovolemicshock(O.7)andallergicreactions(4.6)a
3、效肯定且安全可靠、不良反应少,并对提高临床药物治疗效果有很大意义。【关键词】血细胞分离机;血细胞单采术;血浆置换术ApplicationofHemapheresisonTreatmentofHematologyandObservationoftheAdverseReactionLUQun一.;cian,LJYan—jie,ZHAOYufeng,LIUCan—xia,LZhen—yu,XUKai—lin.DepartmentofHematology,PAffiliatedHospitalofXuzhouMedicalCollege,Xuzhou221002,ChinaC0rrP
4、声0author:XUKai—lin,Email:lihmd@l63.corn[Abstract]ObjectiveToinvestigatetheclinicaleffectoftherapeutichemapheresisandobservetheadversereaction.MethodsCS-3000plusbloodcellseparatorwasusedfortherapeutichemapheresisin524patients.Weselectedthedifferentcellcollectionproceduresaccordingtothepatien
5、tsconditionsandanalyzedtheclinicaleffects,thelaboratoryindexes,theadversereactionsandcorrespondinghandlings.ResultsAftertherapeutichemapheresis,theleucocytecountswasdecreasedfrom(230.1±48.5)×10/Ito(49.3±10.0)×10。/Lin210patientswithhighwhitebloodcell,thehemoglobinwasdecreasedfrom(216.0±23.O)
6、g/Ito(150.0±12.0)g/Landtheerythrocytecountswasdecreasedfrom(7.1±0.5)×1O/Lto(4.3±0.8)×1012/Lin123patientswithpolycythemiavera,theplateletcountswasdecreasedfrom(1080.0±314.O)×10/Ito(341.0±82.0)X10。/Lin158patientswithhighplatelet.Thereweresignificantdifferences(P<0.01)beforeandaftertreatment.T
7、hesignificantimprovementofclinicalsymptomsandlaboratoryindexesweregainedin90.6patientswithTTPaftertherapeuticplasmaticexchangebyCS3000plusbloodcellseparator.Therewereafewincidencesofcitrussaltpoisoning(3.0),hypovolemicshock(O.7)andallergicreactions(4.6)a
此文档下载收益归作者所有