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时间:2020-04-17
《不同类型的QRS波增宽与心力衰竭的相关性.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、中国现代药物应用2014年8月第8卷第16期ChinJM0dDragADo1,Aug2014,Vo1.8,N0.16·5·不同类型的QRS波增宽与心力衰竭的相关性赵杰娉崔天祥方慧玲【摘要】目的探讨不同类型的QRS波增宽与N末端B型脑钠肽前体(NT—proBNP)水平及左心室射血分数(LVEF)的相关性。方法QRS波时限>120ms的慢性心力衰竭患者97例,根据QRS波分为左束支组47例、右束支组50例,非慢性心力衰竭且QRS波时限正常者40例作为对照组。分别测定NT—proBNP水平及LVEF。结果左束支组QRS波时限长于右束支组;左束
2、支组、右束支组NT—proBNP水平明显高于对照组,LVEF低于对照组;左束支组NT—proBNP高于右束支组,LVEF低于右束支组;差异有统计学意义<0.05)。左束支型QRS波时限延长与血浆NT—proBNP水平呈正相关,与LVEF呈负相关。而右束支组QRS波时限延长与血浆NT—proBNP水平呈正相关,与LVEF无明显相关。结论左束支阻滞的QRS波时限延长与左室收缩功能下降及血浆NT—proBNP水平相关性良好,可以作为临床判断心力衰竭程度的一个简便指标。【关键词】QRS波时限;心力衰竭;脑钠肽;左柬支传导阻滞;右柬支传导阻滞Re
3、lativitybetweendifferenttypesofQRScomplexdurationandheartfailureZHAOJie-ping,CUITian—xiang,FangHui—ling.DepartmentofCardiology,HenanChestHospital,Zhengzhou450008,China【Abstract】ObjectiveToinvestigatetherelativityofdifferenttypesofQRScomplexduration(QRSd),N—terminalprobra
4、innatriureticpeptide(NT-proBNP)andleftventricularejectionfraction(LVEF).MetllodsTherewere97patientsofchronicheartfailurewithprolongedQRSdgreaterthan120msdividedintotwogroups.AccordingtotheclinictypesofQRSd,Therewere47casesintheleftbundlebranchblockgroup(LBBB)and50casesin
5、thefightbundlebranchblockgroup(RBBB).Atotalof40caseswithoutchronicheartfailureandunnormalQRScomplexdurationweresetasthecontrolgroup.ThelevelofNT-proBNPandLVEFweremeasured.ResultsTheQRSdofLBBBwaslongerthanthatofRBBB.ThelevelofNT-proBNPofbothLBBBandRBBBwerehigherthanthatof
6、thecontrolgroup,whiletheirLVEFwerelowerthanthatofthecontrolgroup.TheNT—proBNPofLBBBwafthigherthanRBBB,anditsLVEFwaslowerthanRBBB.Thesediferenceswerestatisticallysignificant(P7、VEF.TheprolongedQRSdinRBBBWaSpositivelycorelatedwithNT-proBNP,butwasnotcorrelatedwithLVEF.ConclusionQRSdofleftbundlebranchblockhasgoodrelativitywithLVEFandNT—proBNP,anditcanbeusedasasimpleindicatorofthelevelofheartfailure.【Keywords】QRScomplexduration;Heartfailure;Brainna8、triureticpeptide;Leftbundlebranchblock;Rishtbundlebranchblock心力衰竭(心衰)是影响人类健康的主要疾病之一,有心律失常、急性或未纠正电解质紊乱、使
7、VEF.TheprolongedQRSdinRBBBWaSpositivelycorelatedwithNT-proBNP,butwasnotcorrelatedwithLVEF.ConclusionQRSdofleftbundlebranchblockhasgoodrelativitywithLVEFandNT—proBNP,anditcanbeusedasasimpleindicatorofthelevelofheartfailure.【Keywords】QRScomplexduration;Heartfailure;Brainna
8、triureticpeptide;Leftbundlebranchblock;Rishtbundlebranchblock心力衰竭(心衰)是影响人类健康的主要疾病之一,有心律失常、急性或未纠正电解质紊乱、使
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