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1、国产与进口轻甲II坐嚇滴眼液治疗非感染性结膜炎的比较中国新药与临床杂志2000年第5期第19卷论著作者：陈冬梅吴静安晏晓明惠延年周健张金华单位：陈冬梅吴静安晏晓明(北京医科大学第一医院眼科，北京100034)；惠延年周健(中国人民解放军第四军医大学西京医院眼科，陕西西安710032)；张金华(天津眼科医院，天津300020)关键词：耗甲卩坐嚇；眼药水；变应性结膜炎［摘要］目的：评价国产0.025%耗甲I坐啦滴眼液对非感染性结膜炎的疗效和不良反应。方法：204例非感染性结膜炎病人随机分为国产组103例和进口组101例。国产组用国产0.025%轻甲卩坐I林滴眼液,进口组
2、用进口同类药,3〜4次.d-L疗程7d。结果：国产组总有效率97.1%与进口纽.的9&0%差并无显著意义(P>0.05)o病人有眼干或结膜刺激感，发生率为4.9%及6.8%,与进口组的6.9%及8.9%相似(P>0.05)o本品不引起视力、瞳孔、脉率和血压的改变。结论：国产0.025%释甲II坐咻滴眼液能迅速、有效地缓解非感染性结膜炎的症状和体征，疗效和不良反应发生率与进口同类产品相似。［中图分类号］R977.ll；R777.31［文献标识码］A［文章编号］1007-7669(2000)05-0394-03Domesticandimportedoxymetazoli
3、neophthalmicsolutionsintreatingnon-infectiousconjunctivitisCHENDong-Mei,WUJing-An,YANXiao-Ming(DepartmentofOphthalmology,TheFirstHospitalofBeijingMedicalUniversity,BEIJING100034,China)HUIYan-Nian,ZHOUJian(DepartmentofOphthalmology,XijingHospital,FouthMilitaryMedicalUniversityofPLA,Xi-a
4、nSHANGXI710032,China)ZHANGJin-Hua(TianjinOphthalmologyHospital,TIANJIN300020,China)［ABSTRACT］AIM:Toevaluatetheefficacyofdomestic0.025%oxymetazolineophthalmicsolutionintreatingnon-infectiousconjunctivitis.METHODS:Twohundredandfouroutpatientswithnon-infectiousconjunctivitiswererandomlydi
5、videdintotwogroups・Domesticgroup(103patients)received0.025%domesticoxymetazolineophthalmicsolutionmadeinTianjin;importedgroupreceivedthesamekindofophthalmicsolutionmadeinCanada,tid-qid,for7cLTheeffectandadversereactionwereobserved・RESULTS:Theeffectiverateswere97.1%indomesticgroupand98.
6、0%inimportedgroup(P>0.05).Onlyafewpatientshadcomplaintsofdryeyesorconjunctivalirritantsensation.Patientshadcomplaintsofdryeyesorconjunctivalirritantsensation,4.9%,6.8%indomesticgroupand6.9%,8.9%inimportedgroup,respective!y(P>0.05).Theophthalmicsolutiondidn'teffectvisualacuity,diam
7、eterofpupil,pulseandbloodpressure・Nosignificantdifferenceswerefoundbetweenthesetwogroups・CONCLUSION:Domestic0.025%oxymetazolineophthalmicsolutionwasaseffectiveandsafeastheimportedone.［KEYWORDS］oxymetazoline;ophthalmicsolutions;allergicconjunctivitis非感染性结膜炎主要症状和体征有眼痒、流汨、结膜充血和水肿，病因与感染因
