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时间:2017-12-08
《2型糖尿病合并脑梗死的影响因素分析》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、国际检验医学杂志2014年1月第35卷第2期IntJLabivied,January2014,Vo1.35,No.2·l63··临床检验研究论著·2型糖尿病合并脑梗死的影响因素分析朱明,张凤英,付波,徐吟亚(武钢总医院检验科,湖北武汉430080)摘要:目的探讨2型糖尿病合并脑梗死的相关危险因素。方法检测105例2型糖尿病患者(A组:2型糖尿病合并脑梗死患者45例;B组:单纯2型糖尿病患者6O例)和4O例健康人(c组:健康对照组)的三酰甘油(TG)、总胆固醇(Tc)、高密度脂蛋白胆固醇(HDI一C)、低密度脂蛋白
2、胆固醇(IDI一C)、糖化血红蛋白(HbA1c)、C反应蛋白(CRP)、D二聚体(【)Idimer)水平。通过多元回归分析将各组患者既往史、实验室检测指标等各项临床资料进行统计学分析,以筛选2型糖尿病合并脑梗死的危险因素。结果A、B组高血压病史比例明显高于C组,差异均有统计学意义(P3、计学意义(P<0.05)。结论高血压病史、重度颈动脉狭窄率、TG、TC、LDI一C、HbA1c、CRP、D-dimer为2型糖尿病合并脑梗死的独立危险因素,而HDLC为保护性因素。关键词:糖尿病,2型;脑梗死;危险因素DoI:l0.3969/i.issn.1673—413O.2O14.02.015文献标识码:A文章编号:1673-4l30(2014)020163-02Riskfactorsoftype2diabetescombinedwithcerebralinfarctionZhuMing,ZhangFengy4、ing,F“B0,XaYinya(LaboratoryDepartmentofWJSC0GeneralHospita1.Wuhan,Hubei430080,China)Abstract:ObjectiveToexploretherelatedriskfactorsfortype2diabetesmellituscombinedwithcerebralinfarction.Methods105CaSesofpatientswithtype2diabetes(GroupA:45patientswithcerebral5、infarction,GroupB:60patientswithoutcerebralinfarction)andGroupC:4Ocasesofhealthycontrolwereselected.TG,TC,HDI~C,LDL-C,HbA1c,CRPandD-dimerlevelweredetected.Fhroughthemultipleregressionanalysisgroupsofpatientswithpastmedicalhistory,laboratoryexaminationindexes,6、theclinicalstatisticaldatawasanalyzedtoscreentheriskfactorsoftype2diabetesmellitusandcerebralinfarction.ResultsGroupA.groupBwithhistoryofhypertensionwasnotablyhigherthanthatofgroupC,anddifferencehadstatisticalsignificance(P%0.05).Therateofseverecarotidstenosi7、singroupAwassignificantlyhigherthanthatoffandgroupB.TherateofseverecarotidstenosisingroupBwassignificantlyhigherthanthatofgroupC,andthedifferencehadstatisticalsignificance(P<0.05).GroupApa—tientssetHiT1TG,TC,HDLC,IDI一C,HbA1c,CRP,andD-dimercomparedwithgroupBan8、dgroupC,thedifferencel/vasstatisti—callysignificant(P
3、计学意义(P<0.05)。结论高血压病史、重度颈动脉狭窄率、TG、TC、LDI一C、HbA1c、CRP、D-dimer为2型糖尿病合并脑梗死的独立危险因素,而HDLC为保护性因素。关键词:糖尿病,2型;脑梗死;危险因素DoI:l0.3969/i.issn.1673—413O.2O14.02.015文献标识码:A文章编号:1673-4l30(2014)020163-02Riskfactorsoftype2diabetescombinedwithcerebralinfarctionZhuMing,ZhangFengy
4、ing,F“B0,XaYinya(LaboratoryDepartmentofWJSC0GeneralHospita1.Wuhan,Hubei430080,China)Abstract:ObjectiveToexploretherelatedriskfactorsfortype2diabetesmellituscombinedwithcerebralinfarction.Methods105CaSesofpatientswithtype2diabetes(GroupA:45patientswithcerebral
5、infarction,GroupB:60patientswithoutcerebralinfarction)andGroupC:4Ocasesofhealthycontrolwereselected.TG,TC,HDI~C,LDL-C,HbA1c,CRPandD-dimerlevelweredetected.Fhroughthemultipleregressionanalysisgroupsofpatientswithpastmedicalhistory,laboratoryexaminationindexes,
6、theclinicalstatisticaldatawasanalyzedtoscreentheriskfactorsoftype2diabetesmellitusandcerebralinfarction.ResultsGroupA.groupBwithhistoryofhypertensionwasnotablyhigherthanthatofgroupC,anddifferencehadstatisticalsignificance(P%0.05).Therateofseverecarotidstenosi
7、singroupAwassignificantlyhigherthanthatoffandgroupB.TherateofseverecarotidstenosisingroupBwassignificantlyhigherthanthatofgroupC,andthedifferencehadstatisticalsignificance(P<0.05).GroupApa—tientssetHiT1TG,TC,HDLC,IDI一C,HbA1c,CRP,andD-dimercomparedwithgroupBan
8、dgroupC,thedifferencel/vasstatisti—callysignificant(P
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