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时间:2020-04-12
《《肺炎支原体感染与哮喘相关性的分析》.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、14现代医院2015年6月第l5卷第6期专业技术篇ModemHospitalJun2015Vol15No6肺炎支原体感染与哮喘相关性的分析马艳芳王锐万昕CORRELATIONANALYSISOFMYCOPLASMAPNEUMONlAEINFECTIONANDASTHMAMA咖,WANGRui,WAN【摘要】目的探讨肺炎支原体感染和支气管哮喘相关性,为支气管哮喘的诊治提供理论依据。方法选取在我院就诊的支气管哮喘患儿54例作为观察组,选取同期就诊的单纯上呼吸道感染患儿54例作为对照组。两组患儿均行嗜酸性粒细胞计数、白细胞介素一13(IL一13)、免疫球蛋白IgE以及肺炎支原体抗体(MP—Ig
2、M)的检测。对比两组患儿的MP—IgM检测阳性率。根据观察组MP—IgM检测结果分为MP—IgM阳性组和MP—IgM阴性组,对比MP—IgM阳性组、MP—IgM阴性组和对照组患儿的嗜酸性粒细胞计数、IL一13以及IgE的检测结果。结果观察组MP—IgM检测的阳性率为75.93%,对照组MP—IgM检测的阳性率为27.78%,观察组显著高于对照组(P<0.05);MP—IgM阳性组、MP—IgM阴性组的嗜酸性粒细胞计数、IL—l3水平和IgE水平均显著高于对照组(均P<0.05);MP—IgM阳性组的嗜酸性粒细胞计数水平为(538.184-41.63)x10。/L,IL一13水平为(253
3、.27±40.36)ng/L,IgE水平为(327.13±56.91)kU/L,均显著高于MP—IgM阴性(均P<0.05)。结论哮喘的发病与肺炎支原体的感染有关,临床应加强哮喘患儿的肺炎支原体检测,并加强肺炎支原体的抗感染治疗。【关键词】肺炎支原体支气管哮喘相关性【Abstract】ObjectiveToexploretherelationshipbetweenMycoplasmapneumoniaeinfectionandbronchialasthma,andprovideatheoreticalbasisforthediagnosisandtreatmentofbronchiala
4、sthma.Methods54casesofchildrenwithbronchialasthmawereselectedastheobservationgroup,treatmentofchildrenwithherpesinfectionoftheupperrespiratorytractof54casesasthecontrolgroup.Twogroupsofchildrenwereassayedbyeosinophilcount,interleukin一13(IL一13),immunoglobulinIgE(MP—IgM)andMycoplasmapneumoniaeantib
5、odydetection.ThepositiverateofMP—IgMtestintwogroupswerecompared.Accordingtotheobservationgroup,MP—IgMdetectionresultsweredividedintoMP—IgMpositivegroupandMP—IgMnegativegroup.Positivecontrastgroup,MP—IgMMP—IgMnegativegroupandacontrolgroupofchildrenwitheosinophilcount,IL一13andIgEweredetected.Re-sui
6、tsThepositiverateofMP—IgMinchildrenwithobservationgroupdetectionwas75.93%;ThepositiverateofMP—IgMinchildrenwithcontrolgroupofdetectionwas27.78%;ThepositiverateofMP—IgMdetectioninchil—drenwiththeobservationgroupwassignificantlyhigherthanthecontrolgroup(P<0.05);TheMP—IgMpositivegroup,MP—IgMnegative
7、groupseosinophilcount,thelevelsofIL一13andIgElevelsweresignificantlyhigherthanthatofcontrolgroup(allP<0.05);InMP—IgMpositivegroup,Eosinophilscount(538.18±41.63)x10/L,IL一13level(253.27±40.36)ng/LandIgElevel(327.13±56.91)
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