资源描述:
《血清VEGF、TSGF、SCCA及CEA联合检测在口腔癌诊断中的价值.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、血清VEGF、TSGF、SCCA及CEA联合检测在口腔癌诊断中的价值何海波张志闻谢乐许在叶225001,扬州大学临床医学院·江苏省苏北人民医院口腔科[摘要]检测52例口腔癌患者、40例口腔良性肿瘤患者和22例正常人血清中内皮生长因子(VEGF)、肿瘤相关物质群(TSGF)、鳞癌抗原(SCCA)及癌胚抗原(CEA)的含量.发现门腔癌患者血清中的VEGF、TSGF的表达水平高于其他两组(P<0.05)。SCCA和CEA在口腔癌中的检测结果与另两组差异无显著性(P>0.05)。VEGF、TSGF两项标志在口腔癌患者中有较高的阳性率,联合检测有助于
2、提高口腔癌诊断的敏感性和准确性。VEGF;TSGF;SCCA;CEA;口腔癌SignificanceoftheexaminationofbloodserumVEGF,TSGF,SCCAandCEAinthediagnosisoforalcancerHEHaiboZHANGZhiwenXIELeXUZaiye·708·thelialgrowthfactor(VEGF)inseraoforalandoropharyngealsquamouscellcarcinomapatients[J].AnticancerRes,2010,30(5):176
3、5-1766.@@[6]陈巧伦,梁伊仁,张江江.等TAgNORs、TSGF及SCC检测在头颈肿瘤诊断中的应用[J].癌症,2003,22(5):557-558.@@[7]KuoWR,LeeKW,HoKY,etal.Tissuepolypeptideantigen,carcinoembryonicantigen,carbohydrateantigen,andCA125levelsastumormarkersinsquamouscellcarcinomaoftheheadandneck[J].KaohsiungJMedSci,1999,15(3
4、):152-158.@@[8]KrimmelM,HoffmannJ,KrimmelC,etal.RelevanceofSCC-Ag,CEA,CA19.9andCA125fordiagnosisandfollow-upinoralcancer[J].JCraniomaxillofacSurg,1998,26@@[1]ClarijsR,SchalkwijkL,HofmannUB,etal.Inductionof(4):243-248.vascularendothelialgrowthfactorreceptor-3expressionon@@[
5、9]孔宪涛.肿瘤特异抗原和相关抗原的研究现状及检测tumormicrovasculatureasanewprogressionmarkerinhu[J].中华检验医学杂志,2000,23(1):56-58.mancutaneousmelanoma[J].CancerRes,2002,62(23):@@[10]KurokawaH,YamashitaY,TokudomeS,etal.Combina7059-7065.tionassayfortumormarkersinoralsquamouscellcarcinoma@@[2]梁伊仁,万德森,陈
6、功,等.恶性肿瘤相关物质群(TSGF)[J].JOralMaxillofacSurg,1997,55(9):964-966.的测定及临床评价[J]癌症,2002,21(11):1251-1253.@@[11]TamakoshiK,KikkawaF,ShibataK,etal.Clinicalvalue@@[3]LiuCJ,ChangKW,LinSC,etal.PresurgicalserumlevelsofCA125,CA19-9,CEA,CA72-4,andTPAinborderlineofmatrixmetalloproteinase-
7、9andvascularendothelialgrowthovariantumor[J].GynecolOncol,1996,62(1):67-72.factorinoralsquamouscellcarcinoma[J].OralOncol,2009,45(10):920-925.@@[12]李春艳高文信张茹慧,等.半定量RT-PCR检测口腔鳞@@[4]尚政军,李金荣,李祖兵.舌癌患者血清中VEGF升高的状细胞癌死亡相关蛋白激酶的表达[J].实用口腔医学临床意义[J].中华口腔医学杂志,2002,37(3):166.杂志,2010,26(
8、1):110-112.2010-12-252011-03-04@@[5]FriedrichRE,KlapdorR,HagelC,etal.Vascularendo排龈线在后牙邻面