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ID:5292628
大小:2.75 MB
页数:5页
时间:2017-12-07
《人参皂苷联合强的松治疗系统性红斑狼疮的前瞻性随机双盲对照试验》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、中西医结合学报2010年8月第8卷第8期JournalofChineseIntegrativeMedicine,August2010,Vol·8,No·8OriginalClinicalResearch人参皂苷联合强的松治疗系统性红斑狼疮的前瞻性随机双盲对照试验尤艳利,,封颖璐,蔡青!,管剑龙。,张兰玲,徐美娟:,徐霞,凌昌全1.第二军医大学长海医院针灸推拿教研室,上海2004332.第二军医大学长海医院风湿免疫科,上海200433背景:糖皮质激素治疗系统性红斑狼疮(systemiclupuserythematosus,SIE)的副作
2、用一直是临床医生关注的焦点,我们的前期研究表明人参皂苷可以增强地塞米松的临床疗效。目的:探讨人参皂苷联合强的松对SLE中医证候积分和临床疗效的影响。设计、场所、对象和干预措施:所有病例均为上海长海医院风湿免疫科的门诊及住院sIE患者。采用随机、双盲、对照的方法,60例SLE患者在常规强的松治疗的基础上分别给予人参皂苷胶囊和安慰剂胶囊。疗程为3个月。主要结局指标:观察治疗前后SLE患者的中医证候积分和临床总体疗效。结果:治疗组28例,对照组27例纳入结果分析。治疗组总有效率为89.28,与对照组总有效率66.67相比,差异有统计学意义(
3、P4、vedFebruary5.2O10:acceptedMay7.2010;publishedonlineAugust15,2010.1ndexed/abstractedinandfull—textlink—outatPubMed.JournaltitleinPubMed:ZhongXiYiJieHeXueBao。Freefulltext(HTMIandPDF)isavailableathttp:,//www.jcimjourna1.corn.ForwardlinkingandrefereneelinkingviaCrossRef.D()5、l110.3736/jeim20100806Efficacyofginsenosidescombinedwithprednisoneinpatientswithsystemiclupuserythematosus:aprospective,randomized,double—blind,placebo—controlledtrialYan—liYou,Ying—luFeng,QingCai。,Jian—longGuan,Lan—lingZhang。,Mei—juanXu。,XiaXu。,Chang-quanLing1.Departme6、ntofAcupunctureandMassage.ChanghaiHospita1.SecondMilitaryMedicalUniversity,Shanghai200433.China2.DepartmentofRheumatologyandImmunology.ChanghaiHospita1.SecondMilitaryMedicalUniversity.Shanghai200433,ChinaBackground:ThesideeffectsofglucocorticoidintreatmentofsystemicIupu7、seryfhemalOsus(SLE)havebeenthefocusofdebate,andourpreliminarystudyindicatesthatainsenosidescanenhancetheefficacyofdexamethasone.Obiective:ToobservetheeffectsofginsenosidescombinedwithPrednisoneinSLEpalients.Design,setting,participantsandinterventions:Atotalof60SLEpatien8、tsfromDepartmentofRheumatologyandImmunoloqy.ChanghaiHospitaI,SecondMiIiiaryMedicaIUniversiiY,wererandomIYdivid
4、vedFebruary5.2O10:acceptedMay7.2010;publishedonlineAugust15,2010.1ndexed/abstractedinandfull—textlink—outatPubMed.JournaltitleinPubMed:ZhongXiYiJieHeXueBao。Freefulltext(HTMIandPDF)isavailableathttp:,//www.jcimjourna1.corn.ForwardlinkingandrefereneelinkingviaCrossRef.D()
5、l110.3736/jeim20100806Efficacyofginsenosidescombinedwithprednisoneinpatientswithsystemiclupuserythematosus:aprospective,randomized,double—blind,placebo—controlledtrialYan—liYou,Ying—luFeng,QingCai。,Jian—longGuan,Lan—lingZhang。,Mei—juanXu。,XiaXu。,Chang-quanLing1.Departme
6、ntofAcupunctureandMassage.ChanghaiHospita1.SecondMilitaryMedicalUniversity,Shanghai200433.China2.DepartmentofRheumatologyandImmunology.ChanghaiHospita1.SecondMilitaryMedicalUniversity.Shanghai200433,ChinaBackground:ThesideeffectsofglucocorticoidintreatmentofsystemicIupu
7、seryfhemalOsus(SLE)havebeenthefocusofdebate,andourpreliminarystudyindicatesthatainsenosidescanenhancetheefficacyofdexamethasone.Obiective:ToobservetheeffectsofginsenosidescombinedwithPrednisoneinSLEpalients.Design,setting,participantsandinterventions:Atotalof60SLEpatien
8、tsfromDepartmentofRheumatologyandImmunoloqy.ChanghaiHospitaI,SecondMiIiiaryMedicaIUniversiiY,wererandomIYdivid
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