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《复合螺旋藻多糖对S180荷瘤小鼠免疫功能的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、青岛农业大学学报(自然科学版)31(1):27~30,2014JournalofQingdaoAgriculturalUniversity(NaturalScience)文章编号:1674—148X(2014)01—0027—04复合螺旋藻多糖对$180荷瘤小鼠免疫功能的影响刘永举,贾玉辉,唐超,葛蔚,王清吉(1.青岛农业大学生命科学学院,山东青岛266109;2.山东省高校植物生物技术重点实验室)摘要:将螺旋藻多糖(PSP)与银杏提取物(GBE)按1:1比例配制成复合螺旋藻多糖。昆明种小白鼠随机分为5组(荷瘤对照组、阳性对照组、低剂量组、中剂量组、高剂量组),
2、灌服复合螺旋藻多糖,检测复合制剂对S180荷瘤小鼠免疫功能的影响。结果表明:与对照组相比,灌服低剂量组、中剂量组和高剂量组复合螺旋藻多糖:荷瘤小鼠的碳廓清系数分别提高了13.605,53.061,112.930(p<0.01);吞噬指数分别提高了9.96650,4,14.7650,26.7220(p<0.01);淋巴T细胞增殖率分别提高了3O.47,41.89,87.66(p(O.01);白细胞介素一6含量分别降低了6O.19、62.92和69.42%(p3、显促进作用,并能明显降低IL一6的含量水平。关键词:复合螺旋藻多糖;S180荷瘤小鼠;免疫功能中图分类号:R73-3文献标识码:AD0I:10.3969/J.ISSN.1674—148X.2014.01.007EffectsofCompoundP0lysaccharidesfromSpirulinaPlatensisonImmunityFunctionofS180Tumor-bearingMiceLIUYongju,JIAYuhui,TANGChao,GEWei,WANGQingji。(1.CollegeofLifeScience,QiagdaoAgricult4、uralUniversity,Qingdao266109,China;2.KeyLabofPlantBiotechnologyinUniversitiesofShandong)Abstract:ThepolysaccharidesfromSpirulinaPlatensis(PSP)wascompoundedwiththeefectiveingredientsofGinkgoBiloba(GBE)attheratioof1:1.TheKunMingratswererandomlydividedinto5groups(tumor—bearinggroup,posi5、tivecontrolgroup,low—dosegroup,mediate—dosegroup,high—dosegroup),fedwithcompoundpolysaccharidesfromspirulinaplatensis.TesttheeffectsofcompoundpolysaccharidesfromspirulinaplatensisontheimmunityfunctionofS180tumor-bearingmice.Result:comparedwiththetumor—bearinggroup,thecarbonclearancec6、oefficientoflow—dosegroup。mediate—dosegroupandhigh—dosegroupraised13.605,53.061and112.93(P<0.01)respectively,theswallowingindexofthesegroupsreduced9.9665%,14.765,26.722%(p7、L一6ofthesegroupsre-duced60.19,62.929/6,69.42(p8、sfromspiruli
3、显促进作用,并能明显降低IL一6的含量水平。关键词:复合螺旋藻多糖;S180荷瘤小鼠;免疫功能中图分类号:R73-3文献标识码:AD0I:10.3969/J.ISSN.1674—148X.2014.01.007EffectsofCompoundP0lysaccharidesfromSpirulinaPlatensisonImmunityFunctionofS180Tumor-bearingMiceLIUYongju,JIAYuhui,TANGChao,GEWei,WANGQingji。(1.CollegeofLifeScience,QiagdaoAgricult
4、uralUniversity,Qingdao266109,China;2.KeyLabofPlantBiotechnologyinUniversitiesofShandong)Abstract:ThepolysaccharidesfromSpirulinaPlatensis(PSP)wascompoundedwiththeefectiveingredientsofGinkgoBiloba(GBE)attheratioof1:1.TheKunMingratswererandomlydividedinto5groups(tumor—bearinggroup,posi
5、tivecontrolgroup,low—dosegroup,mediate—dosegroup,high—dosegroup),fedwithcompoundpolysaccharidesfromspirulinaplatensis.TesttheeffectsofcompoundpolysaccharidesfromspirulinaplatensisontheimmunityfunctionofS180tumor-bearingmice.Result:comparedwiththetumor—bearinggroup,thecarbonclearancec
6、oefficientoflow—dosegroup。mediate—dosegroupandhigh—dosegroupraised13.605,53.061and112.93(P<0.01)respectively,theswallowingindexofthesegroupsreduced9.9665%,14.765,26.722%(p7、L一6ofthesegroupsre-duced60.19,62.929/6,69.42(p8、sfromspiruli
7、L一6ofthesegroupsre-duced60.19,62.929/6,69.42(p8、sfromspiruli
8、sfromspiruli
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