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1、LettertotheEditorVeterinaryPathology50(6)954-955MiddleEastRespiratorySyndromeªTheAuthor(s)2013Reprintsandpermission:(MERS)Coronavirus:ANewChallengesagepub.com/journalsPermissions.navDOI:10.1177/0300985813506391vet.sagepub.comforVeterinarians?TheemergenceofMiddleEastrespiratorysyndrom
2、e(MERS)ThisisthestateoftheartinSeptember1,2013.Still,tothebestinSeptember2012,arespiratoryinfectioncausedbyMERSofourknowledge,MERS-CoVhasnotbeendetectedincamels,coronavirus(CoV),abetacoronavirus,isofconcernforthegoats,andotheranimalspecies,possiblywiththeexceptionofglobalhealthcommun
3、ity.MostreportedcasesoccurredinthebatsinMiddleEastcountries.Moreover,sofar,noevidenceofMiddleEast,specificallyinSaudiArabiaandsporadicallyindiseaselinkedtoMERS-CoVhasbeenfoundinanimalspecies.Jordan,UnitedArabEmirates,andQatar.AfewimportedInsuchanemergingscenario,scientistsfromseveral
4、insti-caseshavebeenrecordedinEurope.MERSCoVhascausedtutionsarestrugglingtocollectmorematerial,particularlygloballyatotalof51deathsoutof108laboratory-confirmedfromMiddleEastcountrieswithreportedhumancases,but8humaninfections.Thisinfectionislikelyofzoonoticoriginalsofromotherregionswit
5、hoverlapbetweenbatsandcamels.andthusofrelevancefortheveterinarysector.Althoughthezoonoticlinksarestillunclear,weexpectMERSBetacoronaviruseshavetheirorigininbats,andmanyoftobecomerelevantfortheveterinarycommunity(including9themhavebatsasdefinitivehosts.Thisisthecaseforseverepathologis
6、ts)andaninterestingcasestudyregardingdisease4acuterespiratorysyndromecoronavirus(SARS-CoV)andemergenceatthewildlife-livestock-humaninterface.1somerelatedbatcoronavirusesrecentlyfoundinEurope.3MERS-CoViscomparabletoSARS-CoVinseveralaspects.C.GortazarMERS-CoViseasilyculturedinbat-deriv
7、edcelllines,sug-SaBio-IREC(CSIC-UCLM-JCCM)RondadeToledos.n.6gestingasimilarorigin.Recently,aviruswasidentifiedfrom13005CiudadReal,SpainaTaphozousperforatusbat(familyEmballonuridae)fromSaudiArabiathatshowed100%nucleotideidentitywithJ.Segale´sMERS-CoVinaconservedportionoftheCoVgenome.I
8、fthisCentred
