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1、VIROLOGY176,306-307(1990)RecommendationsoftheCoronavirusStudyGroupfortheNomenclatureoftheStructuralProteins,mRNAs,andGenesofCoronavirusesD.CAVANAGH,,*D.A.BRIAN,L.ENJUANES,~K.V.HOLMES,~M.M.C.L,N,~H.LAUDE,S.G.SIDDELL,~W.SPAAN,~F.TAGUCHI,ANDP.J.TALBOTDivisionofMolecularBiolo
2、gy,AFRCInstituteforAnimalHealth,HoughtonLaboratory,Huntingdon,CambridgeshirePE172DA,UnitedKingdom;DepartmentofMicrobiology,UniversityofTennessee,Knoxville,Tennessee37996-0845;CentrodeBiologiaMolecular(CSIC-UAM),UniversidadAutonoma,CantoBlanco,28049Madrid,Spain;4Department
3、ofPathology,UniformedServicesUniversityoftheHealthSciences,4301JonesBridgeRoad,Bethesda,Maryland20814-4799;DepartmentofMicrobiology,USCSchoolofMedicine,2011ZonalAvenue,LosAngeles,California90033-1054;=INRA,StationdeRecherchesdeVirologieetdlmmunologieMoleculaire,CentredeRe
4、cherchesdeJouy-en-Josas,DomainedeVilvert,78350Jouy-en-Josas.France;InstitutffirVirologieundlmmunbiologiederUniversitatWiirzburg,VersbacherStrasse7,8700Wtirzburg.WestGermany;InstituteofInfectiousDisease&Immunology,VirologyDepartment,StateUniversityofUtrecht,Yalelaan1,P.O.B
5、ox80165,3508TDUtrecht,TheNetherlands;NationalInstituteofNeuroscience,NCNP,4-l-1Ogawahigashi,Kodaira.Tokyo187.Japan;andlnstitutArmand-Frappier,UniversiteduQuebec,VirologyResearchCentre,VilledeLaval,Quebec,CanadaH7N423ReceivedNovember22,1989;acceptedNovember28,1989Wepropose
6、anomenclaturetoreplacethevarioussystemscurrentlyinusetodesignatecoronavirusstructuralproteins,mRNAs,andgenes/openreadingframes.Thenonstructuralproteinshavenotbeenaddressed.oissoAca-demicPress,Inc.SeveralnamesarecurrentlyusedtorefertoeachofThelargesurfaceprojection(spikeor
7、peplomergly-thethreeorfourstructuralproteinsofcoronaviruses,coprotein)haspreviouslybeenreferredtoasS(3)orE2withcorrespondinganddifferentacronyms.Similarly,(4).TheacronymSmaybeusedtodenotetheprimarythemRNAs(reviewedinRefs.(1)and(2))havebeentranslationproductandgenerallytor
8、efertothespikereferredtobynumbersorbyletters.Finally,thegenes/glycoprotein.Insome,thoughnotall,c
