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1、MagazineR227Correspondencecomparativeinsightintotheusingpol1a,N-7aandalsoinaprospectsforacoronavirus-basedpolyphyleticintermixwiththeepidemic[6].Theaffectedanimals3′UTRgenesegment.ThediedoffelineinfectiousperitonitisphylogeneticanalysesindicateaCorona
2、virus(FIP),causedbyafelineclosesimilarityoftheAju-CoVandoutbreakincoronavirus(FCoV,alsocalledtheFCoVstrains,suggestingtheFIPV).Thepresenceofacheetahcheetahvirusiscloselyrelatedto,cheetahs:coronavirus(Aju-CoV,forifnotindistinguishablefrom,Acinonyxjubat
3、uscoronavirus)wasdomesticcatisolates.ThemostLessonsforSARSinferredbaseduponthepresencelikelyscenariotoexplaintheseofFIPVantibodiesandtheresultsisthatFCoVjumpedfromobservationofcoronavirus-likethedomesticcatintothecheetah.AlisonJ.PearksWilkerson,partic
4、les[6,7].IndomesticcatsInterestingly,thetwocheetahsEmmaC.Teeling,JenniferL.FCoVoccursintwovarieties:exportedfromSacramentotoTroyer,GilaKahilaBar-Gal,virulentFIPVwhichcausessevereWinstonhadvisitedtheU.C.DavisMelodyRoelke,LaurieMarker,FIPVantibodymediat
5、edfatalveterinaryhospital,wheremanyJillPecon-SlatteryandStephendiseaseinabout5–10%ofdomesticcatFCoVisolateswereJ.O’Brien1infectedcats,andasubclinicaloriginallyisolated,suggestinganentericfelinecoronavirus(FECV)opportunityforcrossspeciesInNovember2002,
6、aflu-likeinfection.Withinmonthsofarrivaltransmission.outbreakcausedbyacoronavirusofthetwoinfectedcheetahstoComparisonsofSARS-CoV,nowknownasSARS-CoVWinstonSafari,othercheetahsinFCoVandAju-CoVrevealoccurredinGuangdongProvincetheparkfellill.Retrospective
7、importantepidemiologicallessons.inChina.Inthespaceof9monthsserumsamplestestedforFirst,thevirusincheetahsandinthediseasetraveledto29antibodiesdemonstratedthatpriorhumansemergedabruptlyfromcountries,infected8098peopleto1982allcheetahserumweredistinctspe
8、ciesreservoirs[3,4,6].andcaused774deaths[1].Thenegative,butwithinsixmonthsofSecond,incats,cheetahsandSARSepidemicspreadwiththeSacramentocheetahs’arrival,humans,thevirusesarehighlyalarmingspeedamonghealthcare100%ofthecheetahshadcontagious,sprea
