【化学工程与工艺专业】【毕业设计+开题报告+文献综述】罗匹尼罗中间体2-甲基-3-硝基苯乙酸的合成

《【化学工程与工艺专业】【毕业设计+开题报告+文献综述】罗匹尼罗中间体2-甲基-3-硝基苯乙酸的合成》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、（20届）毕业设计罗匹尼罗中间体2-甲基-3-硝基苯乙酸的合成II摘要：2-甲基-3-硝基苯乙酸是合成罗匹尼罗的一种重要中间体。本文主要研究了以2-甲基-3-硝基苯甲酸为原料，经过缩合，还原，溴代，取代，水解五步反应制得目标产物2-甲基-3-硝基苯乙酸，总收率为54.19%，并对目标产物进行了熔点和核磁氢谱表征。关键词：2-甲基-3-硝基苯乙酸；合成；工艺；IIAbstract:2-methyl-3-nitrophenylaceticacidisanimportantintermediateofRopinirole.Inthispaper2-methyl-3-nitro

2、phenylaceticacidwassynthesizedfrom2-methyl-3-nitrobenzoicacidasrawmaterial,throughcondensation,reduction,bromination,substitutionandhydrolysisfivestepstoattainthetargetproduct,thetotalyieldwas54.19%.Inaddition,itsstructureshasbeendeterminedbymeltpointand1HNMRdata.KeyWords：2-methyl-3-nitr

3、ophenylaceticacid;Synthesis;TechnologyII目录摘要................................................................................................................................................ⅠAbstract...........................................................................................

4、..................................................Ⅱ1绪论............................................................................................................................................11.1课题背景......................................................................................

5、...................................21.22-甲基-3-硝基苯乙酸合成方法......................................................................................21.2.1以2-甲基-3-硝基苯甲醛为原料合成.....................................................................21.2.22-甲基-3-硝基苯甲醛微波法合成...............................

6、...........................................32　实验部分................................................................................................................................42.1　仪器.......................................................................................................

7、........................42.2　药品...............................................................................................................................42.3　实验内容.........................................................................................................