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时间:2019-11-28
《泛发性脓疱型银屑病92例临床分析》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、2012^2/1Fek20l21Vol.2(hNo.2中司发肌世属番衾总UQChuijDunmvcneRUOL・匚=泛发性脓疱型银們病92例临床分析牛润亭',卢桂玲S张合恩$[摘要]目的探讨泛发性.昧疱型银盾病(GPP)的请发因欢、临床特征及治疗效果,以炭島临床诊疗水平。方法对2004412月-2010年12月天津市长征医曉皮跌科确诊为GPP总者豹咯床資料进行回颖性分析。结果①女性于均发病年龄(36.66±17.40)岁早于男性(41.53±17.47)岁;有银质病史的GPP患者(GPP畋♦)的平均发病年龄(3
2、6.70±4.00)岁早于无银用病史的OFF患者(GP严-),(40.88±2.04)岁。②70.00%未成年CPP由瘙染引起,29例成年CPP多由不当应用激索引起,GPP®*患者中疔69的由寻常性银肩病转化为本病,但CPps患者中仅有23例;GPP患才伴发肝損害16例•春夏李多发,秋冬李少。③榕皮质激倉治疗如复发半高于非械皮质漱倉治疔俎(P=0・035)。结论感染为GPP厳當见请因■轶皮质激*不推荐为一线治疗方安:.[关後词]银屑病,脓葩;诊翦•并发味,治疔[中图分类号]K75&63[文献标识码]B【文章集号
3、〕1001-7089(2012)02-0129T3ClinicalAnalysisof92casesofGeneralizedPustularPsoriasisNIURun-ling.LUGui-ling",ZHANGHc-cn'(LGradtuiieSchoolFTianjinMedwalUniwrsUyfTiarijin300070,China;2.TianjinLon耳MarchHospital,Tianjin300120^C7u-na;34、ofHebeiMandan0560291China)•"*:Abstract.ObjectiveToanalyse(hrctiologiglGiclor,clinicalsituationandthetberapeuheeffectofgeneralirrdpustularGPP)and(opromoietheclinicallevelofdiagnosisandtherapy・MHlwdJiRetnjHpwiivestudieswasusedtoniwly・*dthevariousof92pafienUwit5、hGPPfrwntheDec.of2004toDec.of2010intheDerma-(olo^yofIx>i)gMarch.Results①Womenwithunaverageageofonset(36.66±17,40)yearsearlierthanmale»(41.53±17.47)years;GPP5*1'averageageofonset(36.70±4.00)yearsearlierthanGPP,M,*(40.88±2.04)years.②70.00%ofminorGPPpatientscau6、sedbyinfectionf33casesofadultGPPpaiientscausedbytheimproperuseofcorticosteroidf69ofCPP^1*patientwereIransfonnetlbypsoriasisvulgaris,butGPP^'patientsonly23cases;GPPpatientsassociatedwithliverdamagewere16cases,moreinspringandainnmtrr.lessinautumnandwinter.@The7、n^currenccratewashigherinlhecorticosteroidgroupthanthatinthrnon-rortiroHtrroidgroup.Conclusionllirmostcommonchum-sof(>PPiwinfretion.itsuggrstr<]thatappropriatedrugtherapyshould)>rclMiMrnba^cdonlhedibca^c^verity・[KeywordsPsoriua.iij;F^tular;Diagnosis;Q)mpara8、ti%e;Therapy泛发性賊疱型银同底山即prdisdpuMubrpsoriafiia.GPP)足一种以全身泛发尤帽性脓疱伴严电全身症状的银網櫛•临床少见。在律們病患苦中,GPP的发柄率虽然低F1%(,1,但病悄帝较危眶,医至发生死亡■治疗困难,反复发作°本研究对2004年12月-201U年12月天律市氏征医院皮肤科确诊的92例GHP住院恵#的临味资料进行回顾性分析,结果报吿如下。
4、ofHebeiMandan0560291China)•"*:Abstract.ObjectiveToanalyse(hrctiologiglGiclor,clinicalsituationandthetberapeuheeffectofgeneralirrdpustularGPP)and(opromoietheclinicallevelofdiagnosisandtherapy・MHlwdJiRetnjHpwiivestudieswasusedtoniwly・*dthevariousof92pafienUwit
5、hGPPfrwntheDec.of2004toDec.of2010intheDerma-(olo^yofIx>i)gMarch.Results①Womenwithunaverageageofonset(36.66±17,40)yearsearlierthanmale»(41.53±17.47)years;GPP5*1'averageageofonset(36.70±4.00)yearsearlierthanGPP,M,*(40.88±2.04)years.②70.00%ofminorGPPpatientscau
6、sedbyinfectionf33casesofadultGPPpaiientscausedbytheimproperuseofcorticosteroidf69ofCPP^1*patientwereIransfonnetlbypsoriasisvulgaris,butGPP^'patientsonly23cases;GPPpatientsassociatedwithliverdamagewere16cases,moreinspringandainnmtrr.lessinautumnandwinter.@The
7、n^currenccratewashigherinlhecorticosteroidgroupthanthatinthrnon-rortiroHtrroidgroup.Conclusionllirmostcommonchum-sof(>PPiwinfretion.itsuggrstr<]thatappropriatedrugtherapyshould)>rclMiMrnba^cdonlhedibca^c^verity・[KeywordsPsoriua.iij;F^tular;Diagnosis;Q)mpara
8、ti%e;Therapy泛发性賊疱型银同底山即prdisdpuMubrpsoriafiia.GPP)足一种以全身泛发尤帽性脓疱伴严电全身症状的银網櫛•临床少见。在律們病患苦中,GPP的发柄率虽然低F1%(,1,但病悄帝较危眶,医至发生死亡■治疗困难,反复发作°本研究对2004年12月-201U年12月天律市氏征医院皮肤科确诊的92例GHP住院恵#的临味资料进行回顾性分析,结果报吿如下。
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