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1、茂苗强心胶囊治疗慢性收缩性心力衰竭42例临床观察作者:黄显南,黄照河,谭志辉,潘征,潘兴寿单位:533000广西百色,右江民族医学院附属医院心研所【摘要】目的观察便苗强心胶囊联合西药治疗中、重度慢性收缩性心力衰竭(CHF)的疗效。方法将84例CHF患者随机分为2组,对照组(42例)给予ACEI类、利尿剂、小剂量倍他斥克片(心功能IV级者心力衰竭控制后开始口服)、小剂量地高辛片等常规治疗左心衰竭;观察组(42例)在对照组治疗基础上加服罠茁强心胶囊(4粒,每日3次),2周吋观察比较2组治疗效果。结杲
2、治疗2周后,观察组心功能改善总有效率、中供证候改善总有•效率、左室射血分数(LVEF)提高率分别为92.9%、95.2%、(25±4)%,而对照组则分别为76.2%、81.0%>(11±3)%,2组比较差异有统计学意义(P<0.05或PV0.01)。2组均未发现明显不良反应。结论罠苗强心胶囊联合曲药治疗中、重度CHF,可以更有效地改善心功能,缓解临床症状,提高左室射血分数,且安全性好。【关键词】罠苗强心胶囊;心力衰竭,收缩性,慢性Clinicalobservation
3、onthetherapeuticeffectofQiliqiangxincapsuleon42casesofchroniccontractiveheartfailureHUANGXiannan,HUANGZhaohe,TANZhihui,etal.HeartResearchInstituteofAffiliatedHospitalofYoujiangNationalityMedicalCollege,Guangxi,Baise533000,China【Abstract]ObjectiveToob
4、servethetherapeuticeffectofQiliqiangxincapsulecombinedwithwesternmedicineonmoderateandseverechroniccontractiveheartfailure(CHF).Methods42patientswithCHFincontrolgroupweretreatedwithACEI,uretica,smalldoseofbetablockertablet(Thepatientswithcardiacfunct
5、ionIVgradedidn'ttakeituntilheartfailurewascontrolled),smalldoseofdigoxin.The42patientsinobservationgroup,onthebasisofcontrolgroup,weretreatedbyQiliqiangxincapsule,fourpillsonce,threetimesaday.Thetherapeuticeffectswereobservedandcomparedaftertwoweektr
6、eatmentinthetwogroups.ResultsAftertwoweektreatment,thetotaleffectiverateofcardiacfunctionimprovement,totaleffectiverateofimprovementofTCMsymptomsandincreasingrateofleftventricleejectionfraction(LVEF)inobservationgroupwere92.9%,95.2%,(25±4)%res
7、pectively,butwhichincontrolgroupwere76.2%,81.0%,(l1±3)%respectively.Therewasasignificantdifferencebetweenthetwogroups(P<0.05orP<0.01).Thesideeffectswerenotfoundinbothgroups.ConclusionInthetreatmentofmoderateandseverechroniccontractiveheartfail
8、ure,Qiliqiangxincapsulecombinedwithwesternmedicine,couldimprovecardiacfunctioneffectively,alleviateclinicalsymptomsandincreaseLVEF,withsafety.【Keywords]Qiliqiangxincapsule;Heartfailure,contractive,chronic慢性收缩性心力衰竭(CHF)是内科常见的危重病、疑难病,是多种器质性心脏病的后期表现,也是器