芪苈强心胶囊治疗慢性收缩性心力衰竭临床疗效观察.doc

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1、罠茄强心胶囊治疗慢性收缩性心力衰竭临床疗效观察(湖南省邵阳市第一人民医院心血管内科湖南邵阳422001)【摘要】目的：研究罠茁强心胶囊在慢性收缩性心力衰竭治疗方面的临床疗效及安全性。方法：将我院2013年2月・2014年6月收治的符合心力衰竭研究标准的160例患者随机分为罠苗强心胶囊治疗组(80例)和常规心宝丸对照组(80例)。8周后进行超声心动图、中医证候疗效、心功能疗效等指标疗效观察，并针对牛活质量及不良反应等指标考究其安全性。结果：(1)心功能疗效:对照组的总有效率为64.2%,治疗组总有效率为73.9%,治疗组疗效明显优于对照组(PV0.05)。(2)中医证

2、候疗效：治疗组显效率和总有效率分别为54.8%和79.5%,对照组分别为37.5%和71.9%,治疗组疗效明显优于对照组(P<0.05)。(3)超声心动图指标：两组LVEF、FS、SV和治疗组CO治疗后较治疗前均升高(P<0.05或P<0・01),治疗组LVEF优于对照组(PV0.05)。(4)生活质量:治疗组对患者牛活质量的改善显著优于对照组(P<0.01)o(5)安全性指标：两组均未见异常变化及出现不良反应。结论：罠茁强心胶囊治疗慢性收缩性心力衰竭疗效不错，H无明显不良反应，安全性较高。【关键词】心力衰竭；慢性收缩性；罠茁强心胶囊；疗效；安全性

3、【中图分类号】R573【文献标识码】A【文章编号】1004-6194(2015)02-0456-02【Abstract]Objective:tostudythestilbeneListrongheartcapsuleinthetreatmentofchronicsystolicheartfailureclinicalcurativeeffectandsafety.Methods:ourhospitalinFebruary2013-June2014wereuptothestandardofheartfailureinthe160patientswererandomly

4、dividedintostilbeneListrongheartcapsuletreatmentgroup(80cases)andnormalhearttreasurebolusofthecontrolgroup(80cases)・AftereightweeksofechocardiographyandcurativeeffectofTCMsyndromecurativeeffect,andcardiacfunctionindexofcurativeeffectobservation,andonthequalityoflifeandadversereactionsu

5、chasfastidiousitssafety.Results:(1)thecardiacfunctioneffect:inthecontrolgrouptotaleffectiveratewas64.2%,treatmentgrouptotaleffectiveratewas73.9%,thecurativeeffectoftreatmentgroupwasobviouslybetterthanthatofcontrolgroup(P<0.05).(2)syndromescurativeeffect:thetreatmentgroupsignificante

6、fficiencyandtotaleffectiveratewere54.8%and79.5%respectively,andthecontrolgroupwere37.5%and71.9%respectively,thecurativeeffectoftreatmentgroupwasobviouslybetterthanthatofcontrolgroup(P<0.05).(3)echocardiographyindex:twogroupsofLVEF,FS,SVCOaftertreatmentthanbeforetreatmentandtreatment

7、groupwerehigher(P<0.05orP<0.01),treatmentgroupLVEFisbetterthanthatofcontrolgroup(P<0.05).(4)thequalityoflife:thetreatmentgrouponpatientsqualityoflifeimprovedsignificantlybetterthanthatofcontrolgroup(P<0.01).(5)safetyindicators:therewerenoabnormalchangesinthetwogroupsandap