澳大利亚ANSTO钼锝发生器

《澳大利亚ANSTO钼锝发生器》由会员上传分享，免费在线阅读，更多相关内容在行业资料-天天文库。

1、Molybdenum[99Mo]/Technetium[99mTc]SterileGeneratorFortheProductionofSodiumPertechnetate[99mTc]Injection(fissionBP)Descriptionthelastelutionbutreachesamaximumapproximately23hoursafterthepreviouselutionwhichisequivalentto87.6percentofTheANSTOHealthGeneratorprovidesameansofobtainingathe99Moact

2、ivityatthattime.Table3showsthe99mTcactivityforasterile,isotonic,additiveandpyrogenfreesolutionofSodiumgivengrowthperiodfollowingcompleteelution,relativetothe99MoPertechnetate99mTcInjection(fission)BP.Thegeneratorcontainsactivitycontainedinthegeneratorattheendofthegrowthperiod.fission-produc

3、tmolybdenum-99(99Mo)fromwhich99mTcisseparatedbyelutionintoevacuatedvials.Table3Thegeneratorconsistsofasealedglassvesselcontaining99GrowthPeriods(hours)99mTc:99Moaluminiumoxide.TheMoisfirmlyboundtothealuminaandasaresult,theeluted99mTccontainsnegligibleamountsof99Mo.10.096Overthelifeofthegene

4、rator,anelutionwillprovideayieldof20.182appoximately90%ofthetheoreticalamountof[99mTc]availablefromthe99Mocontainedwithinthegeneratorvessel.40.32980.546PhysicalCharacteristics240.885Technetium-99m,withaphysicalhalf-lifeof6hours,decaysby480.957isometrictransitionto99Tc.Photonsassociatedwitht

5、histransitionwhichareusefulfordetectionandimagingstudiesarelistedinTable4PhysicalDecayChart99MoTable1.FractionFractionDaysDaysTable1RemainingRemainingPrincipalMean%perMeanEnergy01.00080.133RadiationDisintegration(keV)10.77790.103Gamma-289.1140.520.604100.080Reference:“DAWeber,KFEckerman,LTD

6、illmanandJC30.469110.063Ryman.MIRD:RadionuclideandDecaySchemes.”TheSocietyof40.365120.049NuclearMedicineInc.,NewYork,1989.50.284130.03860.220140.030ExternalRadiation70.171Thespecificgammarayconstantfor99mTcis0.19mGyperMBq-h-1at1cm.Thefirsthalfvaluethicknessofleadfor99mTcisTable50.2mm.Attenu

7、ationbyleadisgiveninthefollowingtable.PhysicalDecayChart99mTcFractionFractionTable2DaysRemainingDaysRemainingShieldThicknessesCoefficientof01.00050.562mmPbAttenuation(approx.)10.89160.5010.20.520.79470.4470.9510-130.70880.3981.810-240.6312.710-33.610-4El