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1、手术联合放疗治疗腮腺腺样囊性癌的疗效观察【摘要】目的：探讨临床治疗腮腺腺样囊性癌的理想方案。方法：根据治疗方案不同将2004年9月-2008年5月江西省肿瘤医院收治的105例腮腺腺样囊性癌患者随机分为观察组55例和对照组50例，观察组给予手术联合放疗治疗，对照组给予单纯手术治疗。治疗结束后，所有患者均接受随访，比较两组患者的复发率、转移率及生存率。结果：观察组复发率、转移率均明显低于对照组，差异均冇统计学意义(P0.05),观察组3年生存率、5年生存率均明显高于对照组，差界均有统计学意义(P<0.05)o结论：与单纯
2、手术相比，手术联合放疗治疗腮腺腺样囊性癌可以获得更佳的远期疗效，该联合方案是治疗腮腺腺样囊性癌的理想选择。【关键词】手术；放疗；腮腺；腺样囊性癌ObservationofEfficacyofSurgeryCombinedwithRadiotherapyintheTreatmentofAdenoidCysticCarcinomaoftheParotidGland/LEFei,LUOWen-zheng,TANGYi-hua.//MedicalInnovationofChirm,2013,10(35)：015-017【Ab
3、stract]Objective：Toinvestigatetheidealregimenforadenoidcysticcareinomaoftheparotidgland.Method：Accordingtothetherapeuticregimen,105patientswithadenoidcysticcarcinomaoftheparotidglandadmittedintotheJiangxiProvincialTumorHospitalfromSeptember2004toMay2008weredivi
4、dedintotheobservationgroupfor55casesandthecontrolgroupfor50cases,andtheobservationgroupreceivedsurgerycombinedwithradiotherapy,whilethecontrolgroupwasgivensurgeryalone.Allpatientswerefol1owedupaftertreatment.Thetwogroupsofpatientswithrecurrencerate,metastasisra
5、teandsurvivalratewerecompared.Result：Therecurreneerateandmetastasisrateoftheobservationgroupweresignificantlylowerthanthoseofthecontrolgrouprespectively,thedifferenceswerestatisticallysignificanl(P0.05),whilethe3-yearand5-yearsurvivalrateoftheobservationgroupwe
6、resignificantlyhigherthanthoseofthecontrolgrouprespectively,thedifferenceswerestatisticallysignificant(P〈0.05)・Conclusion：Comparedwithsurgeryalone,thesurgerycombinedwithradiotherapyisabletogetbetterlong-termcurativeeffectinthetreatmentofadenoidcysticcarcinomaof
7、theparotidgland,andthistherapeuticregimenisanidealchoice.[Keywords]Surgery；Radiotherapy；Parotidgland；AdenoidcysticcarcinomaFirst-authorsaddress：JiangxiProvincialTumorHospital,Nanchang330029,Chinadoi：10.3969/j.issn.1674-4985.2013.35.007腺样囊性癌可以发生于乳腺、涎腺、泪腺、男性前列腺、女
8、性生殖道、气管等部位，其中腮腺是腺样囊性癌最常见的发病部位之一［1-3］。腺样囊性癌一个典型的特征就是具有神经侵袭性，而腮腺腺样囊性癌还易发生转移，约10%的腮腺腺样囊性癌患者发生颈淋巴结转移，30%〜40%病程达到10年的患者发生远处转移，其中以肺转移最为常见［4］,因此腮腺腺样囊性癌在临床上需要积极给予治疗，本研究旨在探讨临床治疗腮腺腺样囊
