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1、了宫肌瘤不同术式对卵巢功能影响的临床研究作者单位:474250河南省镇平县人民医院通讯作者:高琴【摘要】F1的探讨手术治疗子宫肌瘤不同术式对卵巢功能的影响。方法回顾性分析83例手术治疗的子宫肌瘤患者。按术式分为子宫肌瘤剔除术组(D组)、子宫切除+保留附件组(E组)、全子宫切除术+双侧附件切除术组(F纽),比较三组手术前后围绝经期综合征发生率的差异,以及术后E[sub]2【/sub】、FSH的变化。结果三组术前围绝经期综合征症状发生率差异无统计学意义(P>0.05),术后F组发生率(24.8%)显著高于D、E两组(8.7%,12.9
2、%)(P<0.05),E组发生率高于D组(PV0.05)。D组E【sub】2【/sub】、FSH术前为术后比较差异均无统计学意义(P>0.05),E、F两组术后2周E[sub]2【/sub]下降,FSH升高,与术前相比差异均有统计学意义(P<0.05);术后6个月E[sub]2【/sub】、FSH与术询相比差异均无统计学意义(P>0.05)o结论卵巢和子宫对妇女的内分泌十分重要,子宫肌瘤患者行了宫和卵巢切除应慎重考虑。【关键词】子宫肌瘤;手术;卵巢功能Clinicalresearchofdifferentsurgicaluteri
3、nefibroidsonovarianfunctionGAOQin,LVWei-xia,ZHANGYan.People'sHospitalofZhenpingCounty,Zhenping474250,China[Abstract]ObjectiveToinvestigatethesurgicaltreatmentofuterinefibroidswithdifferentsurgicalproceduresonovarianfunctioruMethodsRetrospectiveanalysisof83casesofsurgi
4、caltreatmentofuterinefibroidspatients.Dividedaccordingtosurgicalmyomectomygroup(Dgroup),hysterectomy+retainedattachmentgroup(Egroup),hysterectomy+bilateraloophorectomygroup(Fgroup),comparedthreegroupsbeforeandaftersurgeryinperimenopausaldifferencesintheincidenceofthes
5、yndrome,andpostoperativeE[sub]2【/sub],FSHchange・ResultsThepreoperativesymptomsofmenopausetheincidenceofthesyndrome,nosignificantdifference(P>0.05),theincideneeofpostoperativeFgroup(24.8%)wassignificantlyhigherthanthatofD,Egroups(8.7%,12.9%)(P<0.05),Egroupwashigherthan
6、intheDgroup(P<0.05).DgroupE[sub]2【/sub】,FSHbeforeandaftersurgerywasnosignificantdifferenee(P>0.05),E,Ftwogroupsdecreasedafter2weeksE[sub]2[/sub],FSHincreased,comparedwithbeforesurgeryweresignificantly(P<0<05);6monthsafterE[sub]2[/sub],FSI1comparedwithbeforesurgerynosi
7、gnificantdifference(P>0.05).ConclusionOvariananduterineendocrineveryimportantforwomen,uterinefibroidsweretreatedbyremovaloftheuterusandovariesshouldbecarefullyconsidered・[Keywords]Uterinefibroids;Surgery;Ovarianfunction子宫肌瘤是女性生殖器最常见的良性肿瘤,多见于30〜50岁的妇女,药物治疗有一定的效果,但停药示肌瘤
8、又会继续生长,故手术仍是治疗了宫肌瘤的主要方法[sup][l][/sup]o本文通过对子宫肌瘤患者手术前后性激素的测定及术后围绝经期综合征发牛率的评估,探讨子宫切除及术式对卵巢功能的影响。1资料与方法1.1一般资料本组83例患者为本院2008年6月