早发冠心病急性心肌梗死患者的临床分析

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1、早发冠心病急性心肌梗死患者的临床分析［摘要］冃的：分析早发冠心病(PCAD)急性心肌梗死(AMI)患者的传统危险因素及冠状动脉的病变特点。方法:对98例PCAD-AMI患者(PCAD组)、114例晚发冠心病(LCAD)AMI患者(LCAD组)及82例非冠心病者(非冠组)的传统危险因素及冠状动脉的病变特点进行分析。结果:危险因素分析显示,PCAD组阳性家族史的比率显著高于LCAD组(P〈0.01);PCAD.LCAD两组与非冠组比较，各项危险因素均偏高，差片有统计学意义(P〈0.01或P<0.05)。冠状动脉造影结果显示,PCAD组单支病变比率比

2、LCAD组高(P<0・01)。PCAD组的单支闭塞率与LCAD组相近,未见双支闭塞者oPCADm的每例单个支架置入比率显著高于LCADm(P<0.01)o结论:PCAD-AMI患者的发病与传统危险因索密切相关；PCAD组的冠状动脉病变轻于LOAD组;经皮冠脉介入术是PCAD-AMI患者十分有效的治疗方法么一。［关键词］早发冠心病；急性心肌梗死；冠状动脉病变;危险因素［中图分类号］R541.4E文献标识码］A［文章编号］1673-7210(2010)05(c)-015-03Clinicalanalysisofprematurecoronaryar

3、terydiseaseinpatientswithacutemyocardialinfarctionZHANGXiangqun(DepartmentofCardiology,LinziPeople"sHospitalofZiboCity,Zibo255400,China)［Abstract］Objective:Toanalyzethetraditiormlriskfactorsandcoronarylesioncharacter!stiesofpatientswithprematurecoronaryarterydisease(PCAD)wit

4、hacutemyocardialinfarction(AMI).Methods:Thetraditionalriskfactorsandcoronarylesioncharacteristicsofangiographyandinterventionaltreatmentof98PCAD-AMIpatients(PCADgroup),114late-onsetcoronaryarterydisease(LCAD)AMIpatients(LCADgroup)and82non-coronaryarterydiseasepatients(non-CA

5、Dgroup)wereanalyzed.Results:Riskfactoranalysisshowedthattheratioofpositivefami1yhistoryofPCADgroupwassignificantlyhigherthanthatofLCADgroup(P<0.01);theriskfactorsofPCADgroupandLCADgroupwerehigherthanthoseofnon-CADgroup(P〈0.01orP〈0・05)・Coronaryangiographyresultshowedthatthein

6、cidonceofsingle-vesseldiseaseinPCADgroupwashigherthanthatinLCADgroup(P<0.01).ThesinglevesselocclusionrateofPCADgroupwassimilartothatofLCADgroupandtherewasnodouble-vesselocclusion.ThesinglestentperpatientratioofPCADgroupwassignificantlyhigherthanthatofLCADgroup(P<0.01).Conclu

7、sion:PCAD-AMIiscloselyrelatedtothetraditionalriskfactors・ThecoronarylesionsofPCADgroupare1ighterthanthoseofLCADgroup・PercutaneouscoronaryinterventionisaveryeffectivetreatmentforpatientswithPCAD-AMI.［Keywords］Prematurecoronaryarterydisease;Acutemyocardialinfarction;Coronaryle

8、sion;Riskfactor早发冠心病(PCAD)的定义为：冠心病的发病年龄男性〈55岁，女性〈65岁。冠心病传统的危险因素主要包括早发冠心病家族史