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1、蝉花延缓慢性肾功能衰竭进展的临床观察*【关键词】蝉花；肾功能衰竭，慢性【摘要】目的观察和评价蝉花在临床上对慢性肾功能衰竭(CRF)患者的治疗效果。方法将临床收集的126例CRF患者随机分为蝉花治疗组5=42)、金水宝组(n=42)和西夯対照组(n=42),用药治疗180天,检测CRF患者的残存肾功能(SCnBUN、CCr)、鼎旨(TG、TCH)、血清白蛋白(ALB)、血红蛋白(Hb)、红细胞比积(HCT),通过自身对照和组间对照观察和评价蝉花对CRF的临床疗效。结果蝉花治疗组在治疗肩SCr.BUN比治疗前均明显下降(P<0.01)o蝉花治疗组在治疗后ALB、Hb、HCT均明显高于治疗前，
2、其差异有非常显著性(PvO.Ol)。蝉花治疗组患者治疗后的TG和TCH较治疗前有所改善(P<0.05)。结论蝉花能降低血清肌肝、尿索氮水平，提高肌肝清除率，促述蛋白质的合成，纠正负氮平衡的作用；升高CRF患者血浆白蛋白、血红蛋白量和红细胞比积；能改善CRF患者的片油三酯和降低血清胆固胛水平的作用。【关键词】蝉花；肾功能衰竭，慢性ClinicalobservationoncordycepscicadaeshinginpreventingtheprogressionofchronicrenalfailureJINZhou-hui,CHENYi-ping.DivisionofNephrolog
3、y,ShanghaiLiqunHospital,Shanghai200333,China【Abstract】ObjectiveToobserveandevaluatetheefficiencyofcordycepscicadaeshing(C.C.S.)therapyinthe126patientssufferedfromchronicrenalfailure.MethodsOnehundredandtwenty-threepatientscollectedintheclinicweredividedintoblockdesignmethodC・C・S・treatmentgroup(n=
4、42),Jinshuibaocontrolgroup(n=42),Westernmedicinecontrolgroup(n=42)andwerecured180days.Theremnantrenalfunction(SCr,BUN,CCr),TG,TCH,plasmaalbumin(A1B),hemoglobin(Hb),hematocrit(HCT)ofthepatientswithchronicrenalfailureweredetected・ToobserveandevaluatetheefficiencyofC.C.S.therapyin126patientswithCRFb
5、ytheself-contrastandinter-contrastmethod.ResultsTheBUNandSCrintheC.C.S.treatmentgroupdecreasedsignificantlycomparedtobeforereceivingtherapy(P<0.01)•TheALB,HbandHCTintheC.C.S.treatmentgroupweresignificantlyhigherthanthosebeforereceivingtherapy(P<0.01).TheTGandTCHintheC.C.S.treatmentgroupameliorate
6、d(P<0.05).ConclusionCordycepscicadaeshingamelioratedtherenalfunction,decreasedthelevelofBUNandSCrandincreasedthelevelofcreatinineclearance(CCr)・C.C.S.acceleratedthesynthesisofproteinandcorrectedtheunbalanceofnitrogenousmetabolism・C.C.S.promotedthequantityofHb,HCTandALB.C.C.S.decreasedthelevelofTG
7、andTCHinthepatientwithCRF.【Keywords]cordycepscicadaeshing；renalfailure,chronic慢性肾功能衰竭(CRF)是原发性或继发性慢性肾脏疾患引起肾功能损害和进行性恶化的结果。不同的病凶引起CRF,其进展的速度和程度可有显著差异，一般认为某些原发病尚缺乏特异有效地治疗，病变难以控制，肾功能衰竭进展较快，如膜增殖性肾炎、成人紫瘢性肾炎、糖尿病肾病、多发性骨髓瘤肾病、狼疮
