胞磷胆碱钠片治疗急性脑出血临床疗效

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1、胞磷胆碱钠片治疗急性脑出血临床疗效［摘要］目的探讨胞磷胆碱钠片治疗急性脑出血的临床疗效及安全性。方法将本院住院治疗的急性脑出血患者178例，随机分成治疗组与对照组各89例。对照组患者采用常规的脑出血治疗，治疗组在对照组治疗基础上给予患者胞磷胆碱钠片治疗。结果治疗组与对照组治疗后，神经功能缺损评分均较治疗前有明显改善，但治疗组改善的程度明显大于对照组(P<0.05)o治疗组89例患者的总有效率为95.51%,对照组89例患者的总有效率为69.66%,两组患者总有效率相比，治疗组明显髙于对照组，差异有统计学意义(P<0.05)o结论胞磷胆碱钠片治疗急性脑出血是安全的、有

2、效的，可以有效地改善患者的神经功能，值得在临床广泛推广。［关键词］急性脑出血；胞磷胆碱钠片；临床疗效；安全性［中图分类号］R743.34［文献标识码］A［文章编号］1674—4721(2012)09(c)—0060—02TheclinicalcurativeeffectofciticolinesodiumtabletsinthetreatmentofacutecerebralhemorrhageQIUGuanyangHUANGDandanDENGYaofangWUYongHUANGHanningCUIMingzhiDepartmentofNeurology,theP

3、eople"，sHospitalofGaozhouCityinGuangdongProvince,Gaozhou525200,China[Abstract]ObjectiveTodiscusstheclinicalcurativeeffectandsafetyofciticolinesodiumtabletsinthetreatmentofacutecerebralhemorrhage・MethodsOnehundredandseventy—eightcasesofpatientswithacutecerebralhemorrhagehospitalizedinou

4、rhospitalwererandomlydividedintotreatmentgroupandcontrolgroup(n=89)・Patientsincontrolgroupweregivenconventionaltreatmentforcerebralhemorrhage・Patientsintreatmentgroupweregivenciticolinesodiumtabletsonthebaseofthecontrolgroup.ResuItsAftertreatment,theneuralfunctiondefectscaleofthetreatm

5、entgroupandcontrolgroupwereobviouslyimprovedthanbeforetreatment,whilethedegreeofimprovementinthetreatmentgroupwassignificantlyhigherthanthatinthecontrolgroup(P<0.05)・Thetotaleffectiverateof89patientsofthetreatmentgroupwas95.51%,thetotaleffectiverateof89patientsofthecontrolgroupwas69.66

6、%,thetotaleffectiverateoftwogroupswascompared,andthetreatmentgroupwassignificantlyhigherthanthecontrolgroup，thedifferencewasstatisticallysignificant(P<0.05)・ConclusionThetreatmentofciticolinesodiumtabletsinthetreatmentofacutecerebralhemorrhageissafe,effective,andcaneffectivelyimprovepa

7、/tientswithneuralfunction,itisworthyofclinicalpromotionwidely.[Keywords]Acutecerebralhemorrhage；Citicolinesodiumtablets；Clinicalcurativeeffect；Safety脑出血(ICH)是临床上神经科常见的急性脑血管病，具有很高的病死率和病残率。目前临床上的主要治疗方法为传统的脱水、降颅压、降血压及防治并发症等治疗。脑出血后脑水肿是造成患者脑功能损伤的主要原因，也是脑出血后继发性脑损伤的主要标志[1]。胞磷胆碱(CDP—choline)