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1、老年甲亢40例临床诊治体会【摘要】目的:探讨老年甲亢的临床表现、实验室检査特点及治疗。方法:回顾分析40例6()岁以上老年甲亢的临床资料,在临床表现及实验室检查方面与45例20〜50岁对照组甲亢比较,对接受1311治疗的老年甲亢进行分析。结果:老年甲亢多食、使次增多、烦躁易怒、甲状腺肿大、突眼、血管杂音较対照组少见,而纳差、便秘、抑郁、胫前黏液性水肿及糖尿病、高血压、房颤等合并症较对照组多见;T3、T4升高不如对照组明显,FT3、FT4升高与对照组无差异;29例接受1311治疗的老年甲亢中一次性治愈24例,无甲亢危象发生。结论:老年甲亢缺
2、乏典型性,FT3、FT4更有助于诊断,1311的治疗是安全有效的。【关键词]老年;甲亢;131IDiagnosisandTreatmentof40CasesAgedHyperthyroidismSUOYan-jun(TheFirstPeople'sHospitalofYancheng,JiangsuYancheng224001,China)Abstract:Objective:Tostudytheclinicalmanifestationsandlaboratoryfeaturesandtreatmentofagedhyperthyroi
3、dism・Method:Theclinicalmaterialsoffortycaseshyperthyroidismover60year-oldwererestrospectivelyanalyzed・45caseshyperthyroidismwascomparedwith20〜50year-oldcontrolgrouponclinicalmanifestationsandlaboratorycharacteristics.Thematerialsoftheagedhyperthyroidismwhohadaccepted1311t
4、reatmentwerealsoanalyzed・Result:Comparedwiththecontrolgroupthemanifestationssuchaseatingmore,constantlydefecating,annoyance,easilygettingangry,enlargementofthyroidgland,eyeballprojection,vascularnoisesignificantlydecreased.Whereas,thoseaspoorappetite,constipation,spleen,m
5、ucinosisinthefrontoftibiaandcomplicationssuchasdiabetesmellitus,hypertension,atriumshivergreatlyincreased.HeighteningofT3andT4inagedhyperthyroidismcasesisnotsoobviousasthatincontrolsubjects.ButtherewasnostatisticallydifferenceinheighteningofFT3andFT4•Twenty-fouroftwenty-n
6、inecaseswhohadaccepted1311treatmentwerecuredatfirsttime・Nodangeroussituationofhyperthyroidismhappened.Conclusion:Manifestationsofagedhyperthyroidismlackexponent.MonitoringofFT3andFT4ismorehelpfultodiagnosis・1311treatmentissafeandeffective・Keywords:Aged;Hyperthyroidism;131
7、1甲亢是指多种原因导致甲状腺素分泌过多引起的临床综合征,以20〜40岁多见,但老年甲亢并不罕见,国内统计占甲亢患者4.7〜11.36%[1]。为提高对老年甲亢的认识,将近儿年在我科就诊的40例老年甲亢患者的临床资料进行分析并总结如下。1临床资料1.1一般资料:收集我科2003年3月至2008年12月收治的甲亢患者410例,其中60岁以上老年甲亢40例(9.76%),男性19例,女性21例(男:女=1:1.1),年龄60〜82岁,平均年龄65.50岁。病程3个月至10年,平均2.6年,同时选择同期就诊的20-50岁甲亢患者45例为对照组,病
8、程1个月至3年,平均1.09年。1.2诊断标准:有高代谢症群、甲状腺肿大及眼征。实验室检查T3、T4、FT3、FT4中至少一・项升高,TSH降低或正常。TG、TM正常或升高。1.3实验室激索测