用m—ERG诊断原发性开角型青光眼的初步观察

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1、用m-ERG诊断原发性开角型青光眼的初步观察杨蕾陆豪严良丁琦秦小玲Observationofprimaryopen-angleglaucomadiagonosedbym-ERGYANGLei,LUHao,YANLiang,DINGQi,QINXiao-Ling[Keywords]glaucomaidiagnosis；m-ERG[Abstract]ObjectiveToobservetheprimaryopen-angleglaucoma(POAG)applyingwiththem-ERGfirstord

2、erkernel(FOK)andthesecondorderkernel(SOK).Meth-odsWeusedthemulti-focalelectrophysiologicalexaminationsystem(RETIscan3.15version)andtheOCTOPUSlOlcomputervisualfieldanalysisappliance.Examined33nor-mal-subject-eyesandselected42eyesofglaucomaand16eyesofocular

3、hypertension(suspectedglaucoma)fdividingintoearly»middleandlate-stageglaucoma.FourparametersofPandNwaveoftheamplitudeandlatencyofFOKandSOKwererecorded.TheSPSS8.0softwareofstatisticsanalyzedtheprimarydata-Results(1)Fromthesuspectedtotheearly-stage>middle-

4、stageandlate-stageglaucomagroups*theamplitudeofP-waveandN-wavegraduallydecreasedtthelatencyofP・waveandN-wavegraduallyprolongedi(2>Insumreaction*theamplitudeofP-waveinFOKandamplitudeofN-waveinSOKwassignificantlydifferentintheearly-stage>middle-stageandl

5、ate-stageglaucomagroups*normalcollativegroup(P<0.05)i(3)ThelatencyofN・waveinFOKandthelatencyofP-waveinSOKwassignificantlydifferentbetweenthemiddle-stageandlate-stageglaucomaandnormalcollativegroup(P<0.05)<(4)Inthequadrantalreactionsbetweenthesuspectedgla

6、ucomagroupandnormalcollativegroup»itwassignificantlydifferentinthesuperior-nasalquadrantalP-waveamplitudeinSOKandinterior-nasal•interior-temporalquadrantalN-waveamplitude(P

7、irquadrantalreactions*thantheabnormalityofthevisualfielddamagecanmanifesto[RecAdvOphthalmol2003$23(3)>187-190]【关■词】青先眼'诊斷；多焦视网旗电图收積日期,2002-07-19修回日JW：2OO2-11-2O本文细■，徐刚珍作者简介：杨■•女>1954年7月出生■副主任医师•眼科副主任.联系电话i021-56601100-270(O)作者单位：201900上海市宝山区宝山中心医院眼科Recei

8、veddatesJul19.2002FromtheDepartmentofOphthalmology9BaoshanCentralHospitalofBaoshanDistrict9Shanghai201900【中图分类号】R775.2iR444【文献标识码】A【文章编号】1003-5141（2003）03-0187-04【播要】目的应用多魚视网膜电图（m・ERG〉一阶kernel反应（FOK）和二阶kernel反应（SOK