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1、症状性颅内动脉狭窄行支架治疗疗效分析及研究摘要:口的探究对症状性颅内动脉粥样硬化性狭窄低灌注患者治疗屮,颅内支架置入能否使患者获得较好的临床获益与风险比。方法回顾性分析2010年2月〜2013年11月41例缺血性卒中患者(经脑血管造影显示IAS)患者资料。将患者分为支架组(行颅内支架置入术)、药物组,观察患者围手术期、随访期间主要终点事件。结果手术成功率100%,围手术期大的并发症1例。患者平均随访11.2个月,12月吋对比NIHSS评分好转情况,支架组22例患者,1例术后并发脑梗死后,遗留后遗症,并发症发生率4.5%,12月随访时NIHSS评分较术
2、前增加3分,余21例患者12月随访时平均NIHSS评分下降5.4分。一药物治疗组患者12月随访,卒屮复发率10.5%,1例出院后4月发生再次卒中,12月时NIHSS评分增加4分,1例患者出院8刀后再次卒中,12月WNIHSS评分增加5分,余17例患者12月随访时平均NIHSS评分下降3.8分。具有低灌注特征的颅内置入支架患者更能较好的临床获益。结论对灌注低的症状性MS患者,行颅内支架置入,患者可能获益更多。关键词:症状性颅内动脉狭窄;低灌注;颅内支架置入;脑梗死Symptomaticintracranialarterystenosisstenttre
3、atmentforcurativeeffectanalysisandresearchAbstract:ObjectiveToevaluateintracranialstentonwhetherlowperfusionofsymptomaticIASgreaterbenefit/riskratio.MethodsthepatientsfromJanuaryto2012Decemberon2010inintnicranialstentingretrospectively.Thepatientsweredividedintostentgroup>drugg
4、roup,Observedpatientswithprimaryendpointeventsduringtheperioperativeandfollow-up.Resultsthesuccessfulrateofoperationwas100%,perioperativecomplicationsduringoperationin1cases・Thepatientswerefollowedupforanaverageof11.2months,DecembercomparedwithNIHSSscoreimprovement,22patientsco
5、mplicatedwithcerebralinfarctionstentgroup,1casesofpostoperative,bequeathsequela,thecomplicationratewas4.5%,inDecemberthefollow-upwhencomparedwithpreoperativeNIHSSscoreincreasedby3points,morethan21casesofpatientswithfollow-up,themeanNIHSSscoreinDecemberdropped5.4points・Thedrugth
6、erapygrouppatientswerefollowedupinDecember,strokerecurrenceratewas10.5%,1casesoccurredinAprilagainafterdischargestroke,inDecembertheNIHSSscoreincreased4inAugust,1dischargedpatientsafterstroke,inDecembertheNIHSSscoreincreased5inDecember,morethan17patientswerefollowedupaverageNIH
7、SSscoredecreased3.8points.Thathasalowperfusionfeaturesinpatientswithintracranialimplantationcanbenefit.Conclusion:implantationforpatientswithsymptomaticintracranialarterialstenosisofintracranialstentonperfusiondecreasemaybenefitmore・Keywords:symptomaticintracranialarterystenosi
8、s;lowperfusion;intracranialstenting;cerebralinfarction