尼泊金乙酯合成工艺的探究【毕业论文】

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1、本科毕业论文（20届）尼泊金乙酯合成工艺的探究专业：应用化学摘要：尼泊金乙酯是由对羟基苯甲酸与低级脂肪醇乙醇形成的酯类化合物，是国内外常用的高效食品防腐剂和抑制剂。本文介绍了尼泊金乙酯的应用、性能特点及国内外尼泊金乙酯的研究现状，并从催化剂的角度阐述了几种合成方法合成方法。论文以对羟基苯甲酸和无水乙醇为原料，在催化剂的作用下合成了尼泊金乙酯，并通过对反应催化剂、反应温度、催化剂投料比等条件的选择，探讨了尼泊金乙酯的合成工艺，结果表明，当催化剂选二氯亚砜、对羟基苯甲酸/二氯亚砜的摩尔比为1.0/1

2、.5，反应温度85℃为合成尼泊金乙酯最佳工艺条件，收率达57.5%。关键词：尼泊金乙酯；优化；二氯亚砜StudyonSynthesisofEthylNipaginEsterAbstract:EthylNipaginesterisaesterwhichformedbyp-hydroxybenzoicacidandloweralcoholthatiswidelyusedashighefficiencysafepreservativesandinhibitorathomeandabroad.Thisa

3、rticledescribestheapplicationofethylNipaginesterandit'sappliedandqualitycharacteristicandthestudyonSynthesisofethylNipaginesteronabroad.fromtheperspectiveofthecatalystsynthesismethod,thereareseveralsyntheticmethods.TheprincipleofsynthesisofethylNipag

4、inesterwithphasetransfercatalysisandnowinternaldevelopmentofsyntheticstudyonethylNipaginesterwithphasetransfercatalysiswereemphasized.TheethylNipaginesterwassynthesizedwithp-hydroxybenzoicacidandethanolasrawmaterial,whereaddcatalyst.andthenthebestopt

5、imumsynthesiswasdeterminedbyscreeningtechnologyconditions,whichwaschoosingtheThionylchlorideascatalyst,thep-hydroxybenzoicacid/Thionylchloridemolarratioisthe1.0/1.5,thereactiontemperatureis85℃.Inthebestconditions,thereactionproductyieldto57.5%Keyword

6、s:ethylNipaginester;optimization;thionylchloride目录1引言..............................................................11.1尼泊金乙酯的国内外研究现状......................................11.2尼泊金乙酯合成的催化剂..........................................11.2.1TiSiW12O40/TiO2..

7、...........................................11.2.2壳聚糖磷钨酸盐............................................21.2.3FeCl3·6H2O................................................21.2.4三氧化二钕................................................21.2.5SO42-/TiO2Al2O3......

8、........................................21.2.6大孔强酸性离子交换树脂....................................21.2.7氯化高锡..................................................21.2.8浓硫酸....................................................31.2.9硫氢化钾..........................