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1、动态脑电图对癫痫诊断价值［摘要］目的：探讨动态脑电图(AEEG)对癫痫的诊断价值。方法：对96例癫痫患者和78例非癫痫发作性疾病患者进行常规脑电图(REEG)和AEEG进行对比研究。结果：癫痫组REEG和AEEG的总异常率差异有统计学意义(P<0.01)；癫痫组与非癫痫组AEEG的总异常率差异有统计学意义(P<0.01)；清醒期共出现痫样放电29例(72.5%),睡眠期共出现38例(95.0%),二者比较差异有统计学意义(P<0.01),睡眠期痫样放电多于清醒期。结论：AEEG对癫痫的诊断和鉴别诊
2、断有重要意义。［关键词］癫痫；动态脑电图；癫痫发作；诊断价值［中图分类号］R742.1［文献标识码］A［文章编号］1674-4721(2011)03(c)-045-02ThediagnosticvalueofAEEGtoepilepsyXIAOLi,DINGYuanyingEEGLakeCentralHospitalRoomofXiangtanCity,HunanProvince,Xiangtan411100,China［Abstract］Objective：Toexplorethediagnos
3、ticvalueofAEEGtoepilepsy.Methods：Thecontraststudyofroutineelectroencephalography(REEG)andambulatoryelectroencephalography(AEEG)of96patientswithepilepsyand78patientswithnon-epilepticattackdisorderwereconducted.ResuIts：ThetotalabnormalrateofREEGandAEEGi
4、ngroupepilepsyhadstatisticaldifference(P<0.01).ThetotalabnormalrateofAEEGbetweenepilepsyandnon-epilepticattackdisorderhadstatisticaldifference(P<0.01).29cases(72.5%)occurredepilepticdischargeinawakeperiodandtherewere38casesinsleepperiod(95.0%),ithadsi
5、gnificantdifference(P动态脑电图是目前癫痫的辅助诊断及治疗评价最为有效的手段。动态脑电图对某些神经性症状的鉴别诊断尤为重要，如晕厥、发作性头痛、头昏，可用以鉴别其病源。对于心理原因引起的病症，动态脑电图可确认其心理因素与疾病发作的联系，以明确诊断。临床上动态脑电图可用于脑死亡的判断，此对脏器的移植具有重要意义，还可对颅脑外伤和昏迷及呼吸暂停综合征患者的动态监测，协助判断预后[6-7]o本组资料显示，非癫痫发作性疾病患者AEEG的总异常率为20.5%,且发作间期于睡眠中易出现脑电
6、活动异常，无论临床表现还是脑电变化都提示癫痫有夜间发作倾向。说明虽然癫痫是一种反复性、发作性疾病，但并非在发作性的症状都是癫痫，AEEG可用于癫痫的鉴别诊断。［参考文献］［1］王中原，王晓云，徐运.24小时动态脑电图对发作性意识丧失成年患者的病因诊断价值［J1.山东医药,2010,50(17):89-90.[2]HurYJ,LeeJS,KimDS,etal.Electroencephalographyfeaturesofprimaryepileptogenicregionsinsurgically
7、treatedMRI-negativeinfantilespasms[J]・PediatrNeurosurg,2010,46(3):182-187.[3]FungC,EvansE,ShinD,etal.Hypoxic-ischemicbraininjuryexacerbatesneuronalapoptosisandprecipitatesspontaneousseizuresinglucosetransporterisoform3heterozygousnullmice[J]・JNeurosci
8、Res,2010,88(15):3386-3398.[4]LeeU,OhG,KimS,etal.Brainnetworksmaintainascale-freeorganizationacrossconsciousness,anesthesia,andrecovery：evidenceforadaptivereconfiguration[J].Anesthesiology,2010,113(5):1081-1091.[2]闫四梅，张舒凤，崔莉莉，等•心因性非癫痫性发作的动态脑电图及
