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1、MN1(11.型系统：MN.1(11.型系统是由兰德斯特勒和列维利两人在1927年发现的，它根据红细胞上所含M、N抗原的不同，将人体血液分为M型、N型和MN型三种。红细胞中含有M抗原的为M型，含有N抗原的为N型，MN两种抗原都有的为MN型bduplicaterecessiveepistasischap34)GenesthatarelocatedonthesamechromosomeareAA)linkedB)homologousC)homozygousD)coupled1)WhatdoesGarrod'sHypothesisindic
2、ate?CA)GenesaremadeofDNAB)Humancellscontained23pairsofchromosomesC)ThereisalinkbetweengenesandenzymesD)Enzymesaremadeofproteins2)WhatwasthesignificanceoftheBeadleandTatumExperiment?cA)ItresultedintheCentralDogmaB)ItledtothediscoveryofbredmoldC)Ifresultedintheone-gene-on
3、eenzymehypothesisD)Itledtothediscoveryofthegeneticcode3)Apersonwithsickle-celltraithasatthebeta-globinlocuscA)twowild-typeallelesB)twomutantallelesC)onewild-typeandonemutantalleleD)onewild-typeandonedeletedalleleThevirusfirstshowntohaveRNAasitsgeneticmaterialwastobaccom
4、osaicvirus(TMV)TheHershey-ChaseexperimentinwhichT2phagesgrowninbacteriaonmediacontainingeitherradioactivelylabeledsulfurorradioactivelylabeledphosphorusdemonstratedthatthecoatmaterialofthephagecontrolsthekindofDNAreplicatedinthehostcell.B-DNA、A-DNA、Z-DNA的主要区别：1、A-DNA更紧密
5、,每个碱基平面距离为0.256nm,每圈螺旋有11对碱基,螺距为2.8nm；B-DNA碱基距离为0.338nm,每圈螺旋有10对碱基，螺距为3.4nmo2、C和GZ间核昔酸中脱氧核糖的折叠不同，A-DNA是C3,在内，B-DNA是C2,在内。3、B-DNA大沟、小沟的深度基本是一致的，只是大沟较宽；A-DVA大沟变窄、变深，小沟变宽、变浅。4、Z-DNA糖-磷酸主链的走向呈、'之〃字形，分子呈左手螺旋构象。5、Z-DNA较B-DNA细而舒展，螺旋直径为1.8nm,每个碱基平而距离是0.37nm,每圈含12对碱基,螺距为4.5nmo6、
6、Z-DNA是C3,在内与A-DNA相同。7、Z-DNA仅有一条小沟，且较深，含有较高的负电荷密度。Z-DNA的形成是DNA单链上出现瞟吟与喀咙交替排列所成的。比如CGCGCGCG或者CACACACAo62Inthe1920swhileworkingwithDiplococcuspneumoniae,theagentthatcausespneumonia,Griffithdiscoveredaninterestingphenomenon.Intheexperimentsmicewereinjectedwithdifferenttypes
7、ofbacteria.Foreachofthefollowingbacteriatype(s)injected,indicatewhetherthemicelivedordied:a.typeHRb.typeIIISc.heat-killedIIISd.typeHR+heat-killedIIIS63SeveralyearsafterGriffithdescribedthetransformingprinciple,Avery,MacLeod,andMcCartyinvestigatedthesamephenomenon.a.Desc
8、ribetheirexperiments.b.WhatdidtheirexperimentsdemonstratebeyondGriffith's?c.Howwereenzymesusedasacontrolinthei
