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1、免疫学小总结Chapter1-2:Naturalimmuneresponse:referstotheinnateimmunecellsinthebodyandnaturalimmunemoleculesrecognitionafterantigeniccombinationofpathogensandtheirproductsorotherforeignbody,rapidactivation,biologicaleffects,andgeneratethecorrespondingtopathogenssuchasantigenicityforeignbodyremov
2、alprocess・Adaptiveimmuneresponse:referstothebodyantigenspecificT/Blymphocyteantigenstimulationafteritsactivation,proliferationanddifferentiation,aseffectorcells,thewholeprocessofaseriesofbiologicaleffects・Thecentralimmuneorgans:Itistheplacewhereimmunecellsoccur,develop,differentiateandmat
3、ure:Atthesametime,thedevelopmentofimmuneorgansinforeigncountriesalsoplaysaleadingrole・Thecentralimmuneorgansincludethebonemarrow,thethymus,andthelumen(poultry)Peripheralimmuneorgans:thesitewhereimmunecellssuchasmatureTandBlymphocytesaresettled,alsowheretheimmuneresponseisproduced・Thereare
4、lymphnodes,spleen,lymphatictissueandsubcutaneoustissuerelatedtothemucosa・Lymphocytehoming;Isthedirectionalswimminglymphocytes,includingmaturelymphocytestotheperipherallymphoidorganshoming,lymphocyterecirculation,andlymphocytestoarthritic(suchasskin,intestinalmucosaandjointsynovialinflamma
5、tion)migration.Itsmolecularbasisisthelymphocytesurfacecalledlymphocytichomingreceptors)andthevascularaddressofthecorrespondingelementoftheendothelialcellsinteractwitheachother.Lymphocyterecirculation:lymphocyterecirculationintheperipherallymphoidorgansorlymphoidtissuelymphocytesafterlymph
6、aticenterbloodcirculation,andthroughthecapillariesinperipherallymphoidorgansortissuesaftertheendothelialvenulesreturnstotheperipherallymphoidorgansortissuesinthecirculationprocess・Second,theproblemofThefunctionoftheimmunesystem?Thisincludesimmuneorgans,immunecellsandimmunemolecules・1immun
7、edefense2immunesurveillance,3immuneregulation,4immunestability・Intrinsicandadaptiveimmuneresponsecharacteristicsandthemaincellsinvolved?NaturalimmuneresponseEarly,rapid,withoutmemoryMaincellNKcellsNKTcellsneutrophilsdendriticcellsmononuclearmacrophages・Adaptiveimmun